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Rab11fip5 Gene Detail
Summary
  • Symbol
    Rab11fip5
  • Name
    RAB11 family interacting protein 5 (class I)
  • Synonyms
    9130206P09Rik, D6Ertd32e, GAF1, mKIAA0857, RIP11
  • Feature Type
    protein coding gene
  • IDs
    MGI:1098586
    NCBI Gene: 52055
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:85311944-85351616 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 37.35 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    107 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1098586
 protein coding gene Chr6:85311944-85351663 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030951
 protein coding gene Chr6:86486034-86530930 (-)
A/J MGP_AJ_G0030920
 protein coding gene Chr6:83197144-83239803 (-)
AKR/J MGP_AKRJ_G0030848
 protein coding gene Chr6:85601475-85647666 (-)
BALB/cJ MGP_BALBcJ_G0030930
 protein coding gene Chr6:83188125-83231068 (-)
C3H/HeJ MGP_C3HHeJ_G0030780
 protein coding gene Chr6:98792103-98835085 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031390
 protein coding gene Chr6:88876472-88917576 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028575
 protein coding gene Chr6:81475577-81515773 (-)
CAST/EiJ MGP_CASTEiJ_G0030039
 protein coding gene Chr6:85623043-85665699 (-)
CBA/J MGP_CBAJ_G0030617
 protein coding gene Chr6:92370261-92409197 (-)
DBA/2J MGP_DBA2J_G0030770
 protein coding gene Chr6:82482434-82524063 (-)
FVB/NJ MGP_FVBNJ_G0030723
 protein coding gene Chr6:81686059-81726422 (-)
LP/J MGP_LPJ_G0030849
 protein coding gene Chr6:86487368-86529046 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030759
 protein coding gene Chr6:96560444-96605998 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031414
 protein coding gene Chr6:85410819-85450765 (-)
PWK/PhJ MGP_PWKPhJ_G0029754
 protein coding gene Chr6:81418366-81459858 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029582
 protein coding gene Chr6:84266001-84307239 (-)
WSB/EiJ MGP_WSBEiJ_G0030120
 protein coding gene Chr6:85853686-85896023 (-)



Homology
more
  • Human Ortholog
    RAB11FIP5, RAB11 family interacting protein 5
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RAB11FIP5, RAB11 family interacting protein 5
  • Synonyms
    gaf-1, GAF1, pp75, rab11-FIP5, RIP11
  • Links
    NCBI Gene ID: 26056
    neXtProt AC: NX_Q9BXF6
    UniProt: Q9BXF6

  • Chr Location
    2p13.2; chr2:73073382-73113018 (-)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 2 alleles in 2 genetic backgrounds
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a floxed allele are viable and fertile.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    28
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    760
  • Tissues
    43
  • cDNA Data
    10
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000051343 Ensembl Gene Model | MGI Sequence Detail 39673 C57BL/6J ±  kb
    transcript ENSMUST00000204087 Ensembl | MGI Sequence Detail 6119 Not Applicable  
    polypeptide ENSMUSP00000145402 Ensembl | MGI Sequence Detail 1318 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 11
      cDNA 10
      Primer pair 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:1924936, MGI:2141742
    References
    more
    • Summaries
      All 45
      Developmental Gene Expression 3
      Gene Ontology 7
      Phenotypes 10
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:330636 Iwata S, et al., An efficient i-GONAD method for creating and maintaining lethal mutant mice using an inversion balancer identified from the C3H/HeJJcl strain. G3 (Bethesda). 2021;11(8)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    01/17/2023
    MGI 6.22     		The Jackson Laboratory