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Mettl17 Gene Detail
Summary
  • Symbol
    Mettl17
  • Name
    methyltransferase like 17
  • Synonyms
    2310032K15Rik, D14Ertd209e, Mett11d1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1098577
    NCBI Gene: 52535
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:52122299-52129325 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 26.71 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    152 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1098577
 protein coding gene Chr14:52122299-52130496 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021281
 protein coding gene Chr14:45905358-45914589 (+)
A/J MGP_AJ_G0021238
 protein coding gene Chr14:44712444-44720473 (+)
AKR/J MGP_AKRJ_G0021214
 protein coding gene Chr14:46328374-46336803 (+)
BALB/cJ MGP_BALBcJ_G0021242
 protein coding gene Chr14:44819632-44827665 (+)
C3H/HeJ MGP_C3HHeJ_G0021022
 protein coding gene Chr14:46134463-46142496 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021681
 protein coding gene Chr14:47916211-47927293 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019226
 protein coding gene Chr14:43903192-43910971 (+)
CAST/EiJ MGP_CASTEiJ_G0020541
 protein coding gene Chr14:43093446-43102638 (+)
CBA/J MGP_CBAJ_G0020989
 protein coding gene Chr14:49379343-49387288 (+)
DBA/2J MGP_DBA2J_G0021110
 protein coding gene Chr14:44475042-44483075 (+)
FVB/NJ MGP_FVBNJ_G0021093
 protein coding gene Chr14:44059145-44067398 (+)
LP/J MGP_LPJ_G0021185
 protein coding gene Chr14:46501569-46510669 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021116
 protein coding gene Chr14:48827669-48836743 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021708
 protein coding gene Chr14:45715559-45724312 (+)
PWK/PhJ MGP_PWKPhJ_G0020290
 protein coding gene Chr14:41223352-41231480 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020117
 protein coding gene Chr14:41741051-41748875 (+)
WSB/EiJ MGP_WSBEiJ_G0020594
 protein coding gene Chr14:46014014-46021784 (+)



Homology
more
  • Human Ortholog
    METTL17, methyltransferase like 17
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    METTL17, methyltransferase like 17
  • Synonyms
    METT11D1
  • Links
    NCBI Gene ID: 64745
    neXtProt AC: NX_Q9H7H0
    UniProt: Q9H7H0

  • Chr Location
    14q11.2; chr14:20989806-20997035 (+)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    51
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 52535 NCBI Gene Model | MGI Sequence Detail 7027 C57BL/6J ±  kb
transcript NM_001029990 RefSeq | MGI Sequence Detail 1637 C57BL/6  
polypeptide Q3U2U7 UniProt | EBI | MGI Sequence Detail 461 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 52
    cDNA 51
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:1916887
References
more
  • Summaries
    All 29
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:289070 Shi Z, et al., Mettl17, a regulator of mitochondrial ribosomal RNA modifications, is required for the translation of mitochondrial coding genes. FASEB J. 2019 Nov;33(11):13040-13050
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/14/2023
MGI 6.22 		The Jackson Laboratory