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Anp32a Gene Detail
Summary
  • Symbol
    Anp32a
  • Name
    acidic nuclear phosphoprotein 32 family member A
  • Synonyms
    Anp32, pp32
  • Feature Type
    protein coding gene
  • IDs
    MGI:108447
    NCBI Gene: 11737
  • Alliance
    gene page
  • Transcription Start Sites
    27 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:62248637-62286084 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 33.68 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2000 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_108447
 protein coding gene Chr9:62248575-62286094 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034920
 protein coding gene Chr9:61876223-61918444 (+)
A/J MGP_AJ_G0034900
 protein coding gene Chr9:59844758-59881908 (+)
AKR/J MGP_AKRJ_G0034830
 protein coding gene Chr9:61219993-61261472 (+)
BALB/cJ MGP_BALBcJ_G0034893
 protein coding gene Chr9:59563268-59600639 (+)
C3H/HeJ MGP_C3HHeJ_G0034603
 protein coding gene Chr9:61733076-61770231 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035412
 protein coding gene Chr9:63553885-63598744 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032323
 protein coding gene Chr9:59513949-59550597 (+)
CAST/EiJ MGP_CASTEiJ_G0033924
 protein coding gene Chr9:61868536-61909012 (+)
CBA/J MGP_CBAJ_G0034574
 protein coding gene Chr9:65738259-65777437 (+)
DBA/2J MGP_DBA2J_G0034733
 protein coding gene Chr9:59644217-59681533 (+)
FVB/NJ MGP_FVBNJ_G0034675
 protein coding gene Chr9:58927559-58964688 (+)
LP/J MGP_LPJ_G0034816
 protein coding gene Chr9:62158568-62212433 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034718
 protein coding gene Chr9:67142072-67182020 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035434
 protein coding gene Chr9:61295609-61333720 (+)
PWK/PhJ MGP_PWKPhJ_G0033628
 protein coding gene Chr9:59761145-59799667 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033461
 protein coding gene Chr9:61590831-61632415 (+)
WSB/EiJ MGP_WSBEiJ_G0034037
 protein coding gene Chr9:61218272-61258576 (+)



Homology
more
  • Human Ortholog
    ANP32A, acidic nuclear phosphoprotein 32 family member A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ANP32A, acidic nuclear phosphoprotein 32 family member A
  • Synonyms
    C15orf1, HPPCn, I1PP2A, LANP, MAPM, PHAP1, PHAPI, PP32
  • Links
    NCBI Gene ID: 8125
    UniProt: P39687

  • Chr Location
    15q23; chr15:68778535-68820897 (-)  GRCh38
  • Human Ortholog
    ANP32CP, acidic nuclear phosphoprotein 32 family member C, pseudogene
  • Synonyms
    ANP32C, PP32R1
  • Links
    NCBI Gene ID: 23520
    UniProt: O43423

  • Chr Location
    4q32.3; chr4:164196840-164197821 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotypes from 2 alleles in 2 genetic backgrounds
    4 phenotypes from multigenic genotypes
    17 phenotype references
Homozygous mutant mice are viable, fertile, behaviorally normal, and show no defects of the central nervous system.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    22
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    848
  • Tissues
    120
  • cDNA Data
    83
  • Literature Summary
    6
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 11737 NCBI Gene Model | MGI Sequence Detail 37448 C57BL/6J ±  kb
transcript NM_009672 RefSeq | MGI Sequence Detail 2077 ZRU/MplStud  
polypeptide O35381 UniProt | EBI | MGI Sequence Detail 247 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000004065 acidic leucine-rich nuclear phosphoprotein 32 family member A
    (term hierarchy)
  • PDB
    2JQD
  • InterPro Domains
    IPR045081 Acidic leucine-rich nuclear phosphoprotein 32
    IPR001611 Leucine-rich repeat
    IPR032675 Leucine-rich repeat domain superfamily
  • GlyGen
    O35381 2 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 90
    cDNA 84
    Primer pair 4
    Other 2

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-37491, MGI:2143454
References
more
  • Summaries
    All 55
    Developmental Gene Expression 6
    Gene Ontology 7
    Phenotypes 17
  • Earliest
    J:37303 Chen TH, et al., Structure of pp32, an acidic nuclear protein which inhibits oncogene-induced formation of transformed foci. Mol Biol Cell. 1996 Dec;7(12):2045-56
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory