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Dtymk Gene Detail
Summary
  • Symbol
    Dtymk
  • Name
    deoxythymidylate kinase
  • Synonyms
    CDC8, D10Ertd203e, mtmk, Tmk, TYPK
  • Feature Type
    protein coding gene
  • IDs
    MGI:108396
    NCBI Gene: 21915
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:93720298-93729656 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 47.34 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    39 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_108396
 protein coding gene Chr1:93720298-93730246 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016349
 protein coding gene Chr1:95437024-95449844 (-)
A/J MGP_AJ_G0016330
 protein coding gene Chr1:92023705-92033341 (-)
AKR/J MGP_AKRJ_G0016291
 protein coding gene Chr1:94736451-94746761 (-)
BALB/cJ MGP_BALBcJ_G0016286
 protein coding gene Chr1:92204577-92214272 (-)
C3H/HeJ MGP_C3HHeJ_G0016115
 protein coding gene Chr1:94993078-95002892 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016745
 protein coding gene Chr1:99061410-99074761 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014463
 protein coding gene Chr1:86265287-86274264 (-)
CAST/EiJ MGP_CASTEiJ_G0015698
 protein coding gene Chr1:94324852-94334197 (-)
CBA/J MGP_CBAJ_G0016089
 protein coding gene Chr1:102285423-102294839 (-)
DBA/2J MGP_DBA2J_G0016194
 protein coding gene Chr1:91224343-91233750 (-)
FVB/NJ MGP_FVBNJ_G0016193
 protein coding gene Chr1:90286599-90297029 (-)
LP/J MGP_LPJ_G0016265
 protein coding gene Chr1:96618754-96628088 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016218
 protein coding gene Chr1:105361482-105370874 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016784
 protein coding gene Chr1:94767755-94777969 (-)
PWK/PhJ MGP_PWKPhJ_G0015483
 protein coding gene Chr1:90653901-90663557 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015267
 protein coding gene Chr1:93706299-93715508 (-)
WSB/EiJ MGP_WSBEiJ_G0015758
 protein coding gene Chr1:94583979-94593412 (-)



Homology
more
  • Human Ortholog
    DTYMK, deoxythymidylate kinase
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DTYMK, deoxythymidylate kinase
  • Synonyms
    CDC8, CONPM, PP3731, TMPK, TYMK
  • Links
    NCBI Gene ID: 1841
    neXtProt AC: NX_P23919
    UniProt: P23919

  • Chr Location
    2q37.3; chr2:241675747-241686944 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    25
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    934
  • Tissues
    105
  • cDNA Data
    116
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000026281 Ensembl Gene Model | MGI Sequence Detail 9359 C57BL/6J ±  kb
transcript ENSMUST00000027503 Ensembl | MGI Sequence Detail 1003 Not Applicable  
polypeptide ENSMUSP00000027503 Ensembl | MGI Sequence Detail 212 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 119
    cDNA 118
    Primer pair 1

    Microarray probesets 8
Other
Accession IDs
less
MGD-MRK-37438, MGI:1261792, MGI:2138504
References
more
  • Summaries
    All 46
    Developmental Gene Expression 4
    Gene Ontology 9
    Phenotypes 9
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory