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Rit2 Gene Detail
Summary
  • Symbol
    Rit2
  • Name
    Ras-like without CAAX 2
  • Synonyms
    Rin, Roc2
  • Feature Type
    protein coding gene
  • IDs
    MGI:108054
    NCBI Gene: 19762
  • Alliance
    genome feature page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:31107367-31450181 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 17.69 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    9802 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_108054
 protein coding gene Chr18:31106542-31450343 (-)
129S1/SvImJ ENSMUSG00200015555
 protein coding gene Chr18:28104984-28454174 (-)
A/J ENSMUSG00195002169
 protein coding gene Chr18:28297874-28641750 (-)
AKR/J ENSMUSG00220010785
 protein coding gene Chr18:28248845-28601252 (-)
BALB/cJ ENSMUSG00180003129
 protein coding gene Chr18:28689462-29057112 (-)
C3H/HeJ ENSMUSG00175022347
 protein coding gene Chr18:28219768-28595783 (-)
C57BL/6NJ ENSMUSG00215018307
 protein coding gene Chr18:27976262-28320092 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022060
 protein coding gene Chr18:28342074-28673385 (-)
CAST/EiJ ENSTCUG00005016002
 protein coding gene Chr18:27900305-28245719 (-)
CBA/J ENSMUSG00210016043
 protein coding gene Chr18:28287170-28631006 (-)
DBA/2J ENSMUSG00185022548
 protein coding gene Chr18:28231187-28575056 (-)
FVB/NJ ENSMUSG00205015967
 protein coding gene Chr18:27967450-28242941 (-)
JF1/MsJ ENSUMUG00000016937
 protein coding gene Chr18:28321075-28683411 (-)
LP/J ENSMUSG00230005618
 protein coding gene Chr18:30292436-30641628 (-)
NOD/ShiLtJ ENSMUSG00190006947
 protein coding gene Chr18:28025467-28369294 (-)
NZO/HlLtJ ENSMUSG00225025521
 protein coding gene Chr18:30229131-30572983 (-)
PWK/PhJ ENSLUMG00010003442
 protein coding gene Chr18:28488480-28844229 (-)
SPRET/EiJ ENSMSPG00010020240
 protein coding gene Chr18:28473589-28824064 (-)
WSB/EiJ ENSIUOG00005002643
 protein coding gene Chr18:27980761-28340512 (-)



Homology
more
  • Human Ortholog
    RIT2, Ras like without CAAX 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RIT2, Ras like without CAAX 2
  • Synonyms
    RIBA, RIN, ROC2
  • Links
    NCBI Gene ID: 6014
    UniProt: Q99578

  • Chr Location
    18q12.3; chr18:42743218-43115719 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    70
  • GO References
    16
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    777
  • Tissues
    24
  • cDNA Data
    37
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 19762 NCBI Gene Model | MGI Sequence Detail 342815 C57BL/6J ±  kb
transcript NM_009065 RefSeq | MGI Sequence Detail 1851 Not Specified  
polypeptide P70425 UniProt | EBI | MGI Sequence Detail 217 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 39
    cDNA 38
    Primer pair 1
    Antibodies 1

    Microarray probesets 9
Other
Accession IDs
less
MGD-MRK-37090, MGI:1931467
References
more
  • Summaries
    All 49
    Developmental Gene Expression 4
    Gene Ontology 16
    Phenotypes 6
  • Earliest
    J:36057 Lee CHJ, et al., Rin, a neuron-specific and calmodulin-binding small G-protein, and Rit define a novel subfamily of ras proteins. J Neurosci. 1996 Nov 1;16(21):6784-94
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory