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Sdf2 Gene Detail
Summary
  • Symbol
    Sdf2
  • Name
    stromal cell derived factor 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:108019
    NCBI Gene: 20316
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:78136817-78146310 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 46.74 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    294 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_108019
 protein coding gene Chr11:78136572-78146322 (+)
129S1/SvImJ ENSMUSG00200048647
 protein coding gene Chr11:75253448-75263196 (+)
A/J ENSMUSG00195037969
 protein coding gene Chr11:75132243-75141992 (+)
AKR/J ENSMUSG00220047296
 protein coding gene Chr11:75356167-75365915 (+)
BALB/cJ ENSMUSG00180040639
 protein coding gene Chr11:75321013-75330762 (+)
C3H/HeJ ENSMUSG00175037305
 protein coding gene Chr11:75290256-75300004 (+)
C57BL/6NJ ENSMUSG00215037392
 protein coding gene Chr11:74914263-74924011 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016797
 protein coding gene Chr11:73180188-73189822 (+)
CAST/EiJ ENSTCUG00005044214
 protein coding gene Chr11:74813335-74822928 (+)
CBA/J ENSMUSG00210033374
 protein coding gene Chr11:75108686-75118434 (+)
DBA/2J ENSMUSG00185032241
 protein coding gene Chr11:75378714-75388462 (+)
FVB/NJ ENSMUSG00205030082
 protein coding gene Chr11:75208283-75218031 (+)
JF1/MsJ ENSUMUG00000021609
 protein coding gene Chr11:75757041-75766596 (+)
LP/J ENSMUSG00230042979
 protein coding gene Chr11:76409176-76418924 (+)
NOD/ShiLtJ ENSMUSG00190037367
 protein coding gene Chr11:75425765-75435513 (+)
NZO/HlLtJ ENSMUSG00225037627
 protein coding gene Chr11:78576658-78586406 (+)
PWK/PhJ ENSLUMG00010019963
 protein coding gene Chr11:75282217-75292359 (+)
SPRET/EiJ ENSMSPG00010032835
 protein coding gene Chr11:75691620-75700947 (+)
WSB/EiJ ENSIUOG00005028339
 protein coding gene Chr11:75263372-75273116 (+)



Homology
more
  • Human Ortholog
    SDF2, stromal cell derived factor 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SDF2, stromal cell derived factor 2
  • Links
    NCBI Gene ID: 6388
    UniProt: Q99470

  • Chr Location
    17q11.2; chr17:28648346-28662194 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    16 phenotype references
  • All Mutations and Alleles
    64
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    3
  • Gene trapped
    57
  • Targeted
    3
  • Genomic Mutations
    2 involving Sdf2
  • Find Mice (IMSR)
    30 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    10
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 20316 NCBI Gene Model | MGI Sequence Detail 9494 C57BL/6J ±  kb
transcript NM_001404338 RefSeq | MGI Sequence Detail 1188 C57BL/6  
polypeptide Q9DCT5 UniProt | EBI | MGI Sequence Detail 211 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-37055, MGI:2144317
References
more
  • Summaries
    All 41
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 16
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:375699 Busch T, et al., SDF2 and SDF2L1 are essential co-factors of DNAJB11 for Polycystin-1 processing. J Biol Chem. 2025 Oct 16;301(12):110823
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory