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Sdf2 Gene Detail
Summary
  • Symbol
    Sdf2
  • Name
    stromal cell derived factor 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:108019
    NCBI Gene: 20316
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:78136572-78146322 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 46.74 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    35 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_108019
protein coding gene Chr11:78136572-78146322 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018771
protein coding gene Chr11:79231566-79244181 (+)
A/J MGP_AJ_G0018737
protein coding gene Chr11:76207494-76218259 (+)
AKR/J MGP_AKRJ_G0018707
protein coding gene Chr11:78512051-78521839 (+)
BALB/cJ MGP_BALBcJ_G0018711
protein coding gene Chr11:76613768-76623519 (+)
C3H/HeJ MGP_C3HHeJ_G0018524
protein coding gene Chr11:78552242-78561994 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019162
protein coding gene Chr11:81705958-81718138 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016797
protein coding gene Chr11:73180188-73189822 (+)
CAST/EiJ MGP_CASTEiJ_G0018078
protein coding gene Chr11:78993934-79005970 (+)
CBA/J MGP_CBAJ_G0018494
protein coding gene Chr11:85275668-85286460 (+)
DBA/2J MGP_DBA2J_G0018603
protein coding gene Chr11:75786794-75796794 (+)
FVB/NJ MGP_FVBNJ_G0018593
protein coding gene Chr11:75375015-75384794 (+)
LP/J MGP_LPJ_G0018674
protein coding gene Chr11:79772116-79782772 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018619
protein coding gene Chr11:85685896-85698666 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019202
protein coding gene Chr11:78754815-78764553 (+)
PWK/PhJ MGP_PWKPhJ_G0017849
protein coding gene Chr11:76572578-76584320 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017640
protein coding gene Chr11:78365617-78377140 (+)
WSB/EiJ MGP_WSBEiJ_G0018131
protein coding gene Chr11:78568924-78579502 (+)



Homology
more
  • Human Ortholog
    SDF2, stromal cell derived factor 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SDF2, stromal cell derived factor 2
  • Links
    NCBI Gene ID: 6388
    neXtProt AC: NX_Q99470
    UniProt: Q99470

  • Chr Location
    17q11.2; chr17:28648356-28662189 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotype references
  • All Mutations and Alleles
    62
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    57
  • Targeted
    3
  • Genomic Mutations
    2 involving Sdf2
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 20316 NCBI Gene Model | MGI Sequence Detail 9751 C57BL/6J ±  kb
transcript NM_001404338 RefSeq | MGI Sequence Detail 1188 C57BL/6  
polypeptide Q9DCT5 UniProt | EBI | MGI Sequence Detail 211 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-37055, MGI:2144317
References
more
  • Summaries
    All 35
    Gene Ontology 2
    Phenotypes 15
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:174216 Terzian T, et al., Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models. J Pathol. 2011 Aug;224(4):540-52

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
01/24/2023
MGI 6.22
The Jackson Laboratory