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Ndufv1 Gene Detail
Summary
  • Symbol
    Ndufv1
  • Name
    NADH:ubiquinone oxidoreductase core subunit V1
  • Synonyms
    24 kDa (FP)
  • Feature Type
    protein coding gene
  • IDs
    MGI:107851
    NCBI Gene: 17995
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:4057499-4062755 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 19, 3.72 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    32 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107851
protein coding gene Chr19:4057384-4062806 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024640
protein coding gene Chr19:826191-831447 (-)
A/J MGP_AJ_G0024608
protein coding gene Chr19:786544-791800 (-)
AKR/J MGP_AKRJ_G0024579
protein coding gene Chr19:816304-821560 (-)
BALB/cJ MGP_BALBcJ_G0024606
protein coding gene Chr19:797558-802814 (-)
C3H/HeJ MGP_C3HHeJ_G0024374
protein coding gene Chr19:816701-821957 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025054
protein coding gene Chr19:834871-840127 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022483
protein coding gene Chr19:750813-756182 (-)
CAST/EiJ MGP_CASTEiJ_G0023846
protein coding gene Chr19:828757-834012 (-)
CBA/J MGP_CBAJ_G0024345
protein coding gene Chr19:915801-921057 (-)
DBA/2J MGP_DBA2J_G0024473
protein coding gene Chr19:764273-769529 (-)
FVB/NJ MGP_FVBNJ_G0024440
protein coding gene Chr19:777296-782534 (-)
LP/J MGP_LPJ_G0024560
protein coding gene Chr19:826430-831686 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024471
protein coding gene Chr19:870395-875651 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025102
protein coding gene Chr19:809192-814448 (-)
PWK/PhJ MGP_PWKPhJ_G0023593
protein coding gene Chr19:802589-807815 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023399
protein coding gene Chr19:806466-811723 (-)
WSB/EiJ MGP_WSBEiJ_G0023909
protein coding gene Chr19:802087-807342 (-)



Homology
more
  • Human Ortholog
    NDUFV1, NADH:ubiquinone oxidoreductase core subunit V1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NDUFV1, NADH:ubiquinone oxidoreductase core subunit V1
  • Synonyms
    CI-51K, CI51KD, MC1DN4, UQOR1
  • Links
    NCBI Gene ID: 4723
    neXtProt AC: NX_P49821
    UniProt: P49821

  • Chr Location
    11q13.2; chr11:67605653-67612554 (+)  GRCh38

Human Diseases
more
  • Diseases
    1 with human NDUFV1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 17995 NCBI Gene Model | MGI Sequence Detail 5257 C57BL/6J ±  kb
    transcript NM_133666 RefSeq | MGI Sequence Detail 1608 ZRU/MplStud  
    polypeptide Q91YT0 UniProt | EBI | MGI Sequence Detail 464 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      8 Sequences
    • Protein Ontology
      PR:000011104 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
    • PDB
    • EC
    • InterPro Domains
      IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site
      IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain
      IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily
      IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain
      IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily
      IPR011537 NADH ubiquinone oxidoreductase, F subunit
    Molecular
    Reagents
    less
    • All nucleic 271
      cDNA 267
      Primer pair 3
      Other 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGD-MRK-36428
    References
    more
    • Summaries
      All 56
      Developmental Gene Expression 9
      Gene Ontology 14
      Phenotypes 10
    • Earliest
      J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    last database update
    05/28/2024
    MGI 6.13
    The Jackson Laboratory