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Ppp1r14b Gene Detail
Summary
  • Symbol
    Ppp1r14b
  • Name
    protein phosphatase 1, regulatory inhibitor subunit 14B
  • Synonyms
    AOM172, PHI-1, PLCB3N, Png
  • Feature Type
    protein coding gene
  • IDs
    MGI:107682
    NCBI Gene: 18938
  • Alliance
    gene page
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:6952416-6954692 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 5.12 cM, cytoband A
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107682
 protein coding gene Chr19:6952336-6954692 (+)
129S1/SvImJ no annotation
A/J MGP_AJ_G0024742
 protein coding gene Chr19:3737313-3740632 (+)
AKR/J MGP_AKRJ_G0024715
 protein coding gene Chr19:3859660-3864650 (+)
BALB/cJ MGP_BALBcJ_G0024742
 protein coding gene Chr19:3847691-3849968 (+)
C3H/HeJ MGP_C3HHeJ_G0024510
 protein coding gene Chr19:3983349-3986818 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025188
 protein coding gene Chr19:4162139-4166219 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022622
 protein coding gene Chr19:3644165-3646448 (+)
CAST/EiJ MGP_CASTEiJ_G0023982
 protein coding gene Chr19:3891749-3894028 (+)
CBA/J MGP_CBAJ_G0024482
 protein coding gene Chr19:4213623-4215916 (+)
DBA/2J MGP_DBA2J_G0024609
 protein coding gene Chr19:3710108-3712402 (+)
FVB/NJ no annotation
LP/J MGP_LPJ_G0024695
 protein coding gene Chr19:3933076-3935352 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024604
 protein coding gene Chr19:4121806-4124082 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025236
 protein coding gene Chr19:3994786-3997062 (+)
PWK/PhJ MGP_PWKPhJ_G0023728
 protein coding gene Chr19:3753880-3772385 (+)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0024044
 protein coding gene Chr19:3895325-3898993 (+)



Homology
more
  • Human Ortholog
    PPP1R14B, protein phosphatase 1 regulatory inhibitor subunit 14B
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PPP1R14B, protein phosphatase 1 regulatory inhibitor subunit 14B
  • Synonyms
    PHI-1, PLCB3N, PNG, SOM172
  • Links
    NCBI Gene ID: 26472
    neXtProt AC: NX_Q96C90
    UniProt: Q96C90

  • Chr Location
    11q13.1; chr11:64244479-64246943 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    862
  • Tissues
    104
  • cDNA Data
    252
  • Literature Summary
    8
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 18938 NCBI Gene Model | MGI Sequence Detail 2277 C57BL/6J ±  kb
transcript NM_008889 RefSeq | MGI Sequence Detail 919 C57BL/6  
polypeptide Q62084 UniProt | EBI | MGI Sequence Detail 147 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 253
    cDNA 253

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-36257
References
more
  • Summaries
    All 36
    Developmental Gene Expression 8
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:33574 Lagercrantz J, et al., Sequence and expression of the mouse homologue to human phospholipase C beta3 neighboring gene. Biochem Biophys Res Commun. 1996 Jun 14;223(2):335-40
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory