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Larp7 Gene Detail
Summary
  • Symbol
    Larp7
  • Name
    La ribonucleoprotein 7, transcriptional regulator
  • Synonyms
    C330027G06Rik, D3Wsu161e
  • Feature Type
    protein coding gene
  • IDs
    MGI:107634
    NCBI Gene: 28036
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:127330363-127346998 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 56.54 cM, cytoband H1
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    466 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107634
 protein coding gene Chr3:127330363-127346998 (-)
129S1/SvImJ ENSMUSG00200002560
 protein coding gene Chr3:124071019-124087851 (-)
A/J ENSMUSG00195007789
 protein coding gene Chr3:124209697-124226528 (-)
AKR/J ENSMUSG00220021641
 protein coding gene Chr3:122644744-122661381 (-)
BALB/cJ ENSMUSG00180003563
 protein coding gene Chr3:124136864-124153698 (-)
C3H/HeJ ENSMUSG00175012988
 protein coding gene Chr3:123690538-123707368 (-)
C57BL/6NJ ENSMUSG00215016227
 protein coding gene Chr3:124475700-124492340 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025613
 protein coding gene Chr3:120831482-120847223 (-)
CAST/EiJ ENSTCUG00005003406
 protein coding gene Chr3:124761981-124778494 (-)
CBA/J ENSMUSG00210003743
 protein coding gene Chr3:124313772-124330603 (-)
DBA/2J ENSMUSG00185025093
 protein coding gene Chr3:124928554-124945192 (-)
FVB/NJ ENSMUSG00205023706
 protein coding gene Chr3:123273721-123290360 (-)
JF1/MsJ ENSUMUG00000024551
 protein coding gene Chr3:123682040-123698871 (-)
LP/J no annotation
NOD/ShiLtJ ENSMUSG00190001413
 protein coding gene Chr3:125318148-125334762 (-)
NZO/HlLtJ ENSMUSG00225002003
 protein coding gene Chr3:129363320-129379955 (-)
PWK/PhJ ENSLUMG00010015172
 protein coding gene Chr3:123703255-123720093 (-)
SPRET/EiJ ENSMSPG00010012124
 protein coding gene Chr3:124618968-124636582 (-)
WSB/EiJ ENSIUOG00005016357
 protein coding gene Chr3:124492062-124508701 (-)



Homology
more
  • Human Ortholog
    LARP7, La ribonucleoprotein 7, transcriptional regulator
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LARP7, La ribonucleoprotein 7, transcriptional regulator
  • Synonyms
    ALAZS, HDCMA18P, hLARP7, PIP7S
  • Links
    NCBI Gene ID: 51574
    UniProt: Q4G0J3

  • Chr Location
    4q25; chr4:112636990-112657858 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    23 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null mutation display complete perinatal lethality and a decrease in primordial germ cell number and proliferation.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    40
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    682
  • Tissues
    45
  • cDNA Data
    22
  • Literature Summary
    16
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 28036 NCBI Gene Model | MGI Sequence Detail 16636 C57BL/6J ±  kb
transcript NM_138593 RefSeq | MGI Sequence Detail 2135 ZRU/MplStud  
polypeptide Q05CL8 UniProt | EBI | MGI Sequence Detail 570 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 28
    cDNA 22
    Primer pair 5
    Other 1
    Antibodies 2

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-36208, MGI:1915530
References
more
  • Summaries
    All 66
    Developmental Gene Expression 16
    Diseases 1
    Gene Ontology 8
    Phenotypes 23
  • Earliest
    J:34518 Kerr SM, et al., Ott, a mouse X-linked multigene family expressed specifically during meiosis. Hum Mol Genet. 1996 Aug;5(8):1139-48
  • Latest
    J:388209 Fang Y, et al., Enhanced P-TEFb activity compromises dentate gyrus neurogenesis in mice. EMBO J. 2026 May;45(9):3102-3123
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory