Mela Pseudogene Detail

Summary

• Symbol
  Mela
• Name
  melanoma antigen
• Synonyms
  80kDa

• Feature Type
  pseudogene
• IDs
  MGI:107565
  NCBI Gene: 17276
• Alliance
  gene page
• Transcription Start Sites
  17 TSS

Location &
Maps

• Sequence Map
  Chr8:124152612-124161002 bp, - strand

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 8, Syntenic
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  33 from dbSNP Build 142
• Strain Annotations
  1

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_107565	pseudogene	Chr8:124152612-124161002 (-)
129S1/SvImJ	no annotation
A/J	no annotation
AKR/J	no annotation
BALB/cJ	no annotation
C3H/HeJ	no annotation
C57BL/6NJ	no annotation
CAROLI/EiJ	no annotation
CAST/EiJ	no annotation
CBA/J	no annotation
DBA/2J	no annotation
FVB/NJ	no annotation
LP/J	no annotation
NOD/ShiLtJ	no annotation
NZO/HlLtJ	no annotation
PWK/PhJ	no annotation
SPRET/EiJ	no annotation
WSB/EiJ	no annotation

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype reference
  

• All Mutations and Alleles
  1
• Gene trapped
  1
• Find Mice (IMSR)
  0 strains or lines available

Expression

• Assay Results
  25
• Tissues
  3
• cDNA Data
  12
• Literature Summary
  2

Images

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO

Sequences &
Gene Models

• All Sequences
  27
• UniProt
  7

• NCBI Gene
  17276

Representative Sequences			Length	Strain/Species
transcript	AK090125	GenBank | ENA | DDBJ | MGI Sequence Detail	12349	C3H
polypeptide	P70355	UniProt | EBI | MGI Sequence Detail	1734	Not Applicable

Protein
Information

• UniProt
  7 Sequences
• InterPro Domains
  IPR001969 Aspartic peptidase, active site
  IPR021109 Aspartic peptidase domain superfamily
  IPR003036 Core shell protein Gag P30
  IPR043502 DNA/RNA polymerase superfamily
  IPR008981 F-MuLV receptor-binding
  IPR039464 Gag-Pol polyprotein, Zinc-finger like domain
  IPR002079 Gag polyprotein, inner coat protein p12
  IPR036946 Gamma-retroviral matrix domain superfamily
  IPR000840 Gamma-retroviral matrix protein
  IPR001584 Integrase, catalytic core
  IPR040643 Murine leukemia virus integrase, C-terminal
  IPR001995 Peptidase A2A, retrovirus, catalytic
  IPR018061 Retropepsins
  IPR010999 Retroviral matrix protein
  IPR008919 Retrovirus capsid, N-terminal
  IPR043128 Reverse transcriptase/Diguanylate cyclase domain
  IPR000477 Reverse transcriptase domain
  IPR041577 Reverse transcriptase/retrotransposon-derived protein, RNase H-like domain
  IPR002156 Ribonuclease H domain
  IPR012337 Ribonuclease H-like superfamily
  IPR036397 Ribonuclease H superfamily
  IPR018154 TLV/ENV coat polyprotein
  IPR001878 Zinc finger, CCHC-type
  IPR036875 Zinc finger, CCHC-type superfamily

Molecular
Reagents

• All nucleic 12

  cDNA 12

  
  

  Microarray probesets 5

Other
Accession IDs

MGD-MRK-36137

References

• Summaries
  All 16

  Developmental Gene Expression 2

  Phenotypes 1
• Earliest
  J:1820 Hayashi H, et al., Molecular cloning and characterization of the gene encoding mouse melanoma antigen by cDNA library transfection. J Immunol. 1992 Aug 15;149(4):1223-9
• Latest
  J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

TSS for Mela:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr83368	Chr8:124159365-124159372 (-)	1,633 bp
Tssr83367	Chr8:124159352-124159358 (-)	1,647 bp
Tssr83366	Chr8:124159292-124159301 (-)	1,705 bp
Tssr83365	Chr8:124159171-124159178 (-)	1,827 bp
Tssr83364	Chr8:124159091-124159094 (-)	1,909 bp
Tssr83363	Chr8:124159018-124159028 (-)	1,979 bp
Tssr83362	Chr8:124156334-124156338 (-)	4,666 bp
Tssr83361	Chr8:124156185-124156188 (-)	4,815 bp
Tssr83360	Chr8:124155811-124155820 (-)	5,186 bp
Tssr83359	Chr8:124155704-124155711 (-)	5,294 bp
Tssr83358	Chr8:124154841-124154851 (-)	6,156 bp
Tssr83357	Chr8:124154576-124154587 (-)	6,420 bp
Tssr83356	Chr8:124154461-124154468 (-)	6,537 bp
Tssr83355	Chr8:124154384-124154398 (-)	6,611 bp
Tssr83354	Chr8:124154297-124154305 (-)	6,701 bp
Tssr2728	Chr8:124154212-124154219 (-)	6,786 bp
Tssr83353	Chr8:124153476-124153478 (-)	7,525 bp