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Spag7 Gene Detail
Summary
  • Symbol
    Spag7
  • Name
    sperm associated antigen 7
  • Synonyms
    FSA-1, Fsa1l, MGC:67704
  • Feature Type
    protein coding gene
  • IDs
    MGI:107380
    NCBI Gene: 216873
  • Alliance
  • Transcription Start Sites
    5 TSS
  • Candidate for QTL
    8 QTL
Location &
Maps
more
  • Sequence Map
    Chr11:70554597-70560242 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 11, 43.21 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    64 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107380
protein coding gene Chr11:70554595-70560242 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018611
protein coding gene Chr11:71207219-71212863 (-)
A/J MGP_AJ_G0018579
protein coding gene Chr11:68518342-68523987 (-)
AKR/J MGP_AKRJ_G0018548
protein coding gene Chr11:70575549-70581181 (-)
BALB/cJ MGP_BALBcJ_G0018551
protein coding gene Chr11:68827526-68833170 (-)
C3H/HeJ MGP_C3HHeJ_G0018364
protein coding gene Chr11:70594212-70599856 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019002
protein coding gene Chr11:73367118-73372763 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016647
protein coding gene Chr11:65425920-65431564 (-)
CAST/EiJ MGP_CASTEiJ_G0017919
protein coding gene Chr11:70865495-70872570 (-)
CBA/J MGP_CBAJ_G0018336
protein coding gene Chr11:76671240-76676884 (-)
DBA/2J MGP_DBA2J_G0018446
protein coding gene Chr11:68091523-68097184 (-)
FVB/NJ MGP_FVBNJ_G0018436
protein coding gene Chr11:67732283-67737928 (-)
LP/J MGP_LPJ_G0018516
protein coding gene Chr11:71789311-71794943 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018459
protein coding gene Chr11:77222865-77228507 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019044
protein coding gene Chr11:70834415-70840061 (-)
PWK/PhJ MGP_PWKPhJ_G0017693
protein coding gene Chr11:68738731-68744376 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017483
protein coding gene Chr11:70648759-70656840 (-)
WSB/EiJ MGP_WSBEiJ_G0017973
protein coding gene Chr11:70492748-70498394 (-)



Homology
more
  • Human Ortholog
    SPAG7, sperm associated antigen 7
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SPAG7, sperm associated antigen 7
  • Synonyms
    ACRP, FSA-1
  • Links
    NCBI Gene ID: 9552
    UniProt: O75391

  • Chr Location
    17p13.2; chr17:4959226-4967817 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    17 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000018287 Ensembl Gene Model | MGI Sequence Detail 5646 C57BL/6J ±  kb
    transcript ENSMUST00000018431 Ensembl | MGI Sequence Detail 1159 Not Applicable  
    polypeptide ENSMUSP00000018431 Ensembl | MGI Sequence Detail 227 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 70
      Genomic 1
      cDNA 69

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGD-MRK-35847
    References
    more
    • Summaries
      All 41
      Phenotypes 17
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:357463 Flaherty SE 3rd, et al., SPAG7 deletion causes intrauterine growth restriction, resulting in adulthood obesity and metabolic dysfunction. Elife. 2024 Jul 26;12

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    03/25/2025
    MGI 6.24
    The Jackson Laboratory