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Lsg1 Gene Detail
Summary
  • Symbol
    Lsg1
  • Name
    large 60S subunit nuclear export GTPase 1
  • Synonyms
    D16Bwg1547e
  • Feature Type
    protein coding gene
  • IDs
    MGI:107236
    NCBI Gene: 224092
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:30380187-30406430 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 21.34 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    994 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107236
 protein coding gene Chr16:30379312-30406430 (-)
129S1/SvImJ ENSMUSG00200035477
 protein coding gene Chr16:27395932-27423039 (-)
A/J ENSMUSG00195027258
 protein coding gene Chr16:26945326-26972430 (-)
AKR/J ENSMUSG00220027586
 protein coding gene Chr16:27228703-27255796 (-)
BALB/cJ ENSMUSG00180025470
 protein coding gene Chr16:27166370-27193471 (-)
C3H/HeJ ENSMUSG00175036548
 protein coding gene Chr16:27314053-27341154 (-)
C57BL/6NJ ENSMUSG00215011897
 protein coding gene Chr16:27183517-27210623 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020648
 protein coding gene Chr16:27595133-27622576 (-)
CAST/EiJ ENSTCUG00005033388
 protein coding gene Chr16:27587566-27615181 (-)
CBA/J ENSMUSG00210036266
 protein coding gene Chr16:27356077-27383180 (-)
DBA/2J ENSMUSG00185018071
 protein coding gene Chr16:27271522-27298625 (-)
FVB/NJ ENSMUSG00205014616
 protein coding gene Chr16:27282045-27309144 (-)
JF1/MsJ ENSUMUG00000034267
 protein coding gene Chr16:27446623-27474630 (-)
LP/J ENSMUSG00230030885
 protein coding gene Chr16:29840401-29867502 (-)
NOD/ShiLtJ ENSMUSG00190025204
 protein coding gene Chr16:27460624-27487723 (-)
NZO/HlLtJ ENSMUSG00225039260
 protein coding gene Chr16:33077480-33104625 (-)
PWK/PhJ ENSLUMG00010030220
 protein coding gene Chr16:27277950-27306203 (-)
SPRET/EiJ ENSMSPG00010016514
 protein coding gene Chr16:27245779-27271998 (-)
WSB/EiJ ENSIUOG00005031588
 protein coding gene Chr16:27430054-27457375 (-)



Homology
more
  • Human Ortholog
    LSG1, large 60S subunit nuclear export GTPase 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LSG1, large 60S subunit nuclear export GTPase 1
  • Links
    NCBI Gene ID: 55341
    UniProt: Q9H089

  • Chr Location
    3q29; chr3:194640791-194672463 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    32
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    65
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 224092 NCBI Gene Model | MGI Sequence Detail 26244 C57BL/6J ±  kb
transcript NR_184411 RefSeq | MGI Sequence Detail 2399 ZRU/MplStud  
polypeptide Q3UM18 UniProt | EBI | MGI Sequence Detail 644 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 66
    cDNA 65
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-35701, MGI:2146341
References
more
  • Summaries
    All 39
    Gene Ontology 7
    Phenotypes 11
  • Earliest
    J:44483 Brady KP, et al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. Genome Res. 1997 Nov;7(11):1085-93
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory