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Msx3 Gene Detail
Summary
  • Symbol
    Msx3
  • Name
    msh homeobox 3
  • Feature Type
    protein coding gene
  • IDs
    MGI:106587
    NCBI Gene: 17703
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:139626070-139629001 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 85.04 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    181 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_106587
 protein coding gene Chr7:139626070-139629002 (-)
129S1/SvImJ ENSMUSG00200042495
 protein coding gene Chr7:126190682-126193614 (-)
A/J ENSMUSG00195032300
 protein coding gene Chr7:130673053-130675985 (-)
AKR/J ENSMUSG00220033857
 protein coding gene Chr7:124137783-124140711 (-)
BALB/cJ ENSMUSG00180029257
 protein coding gene Chr7:127365306-127368238 (-)
C3H/HeJ ENSMUSG00175033161
 protein coding gene Chr7:128093590-128096522 (-)
C57BL/6NJ ENSMUSG00215042992
 protein coding gene Chr7:127360068-127363000 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030627
 protein coding gene Chr7:142117324-142120255 (-)
CAST/EiJ ENSTCUG00005050334
 protein coding gene Chr7:130644695-130647622 (-)
CBA/J ENSMUSG00210026472
 protein coding gene Chr7:127820157-127823091 (-)
DBA/2J ENSMUSG00185015773
 protein coding gene Chr7:132130118-132133050 (-)
FVB/NJ ENSMUSG00205026080
 protein coding gene Chr7:127816833-127819765 (-)
JF1/MsJ ENSUMUG00000046222
 protein coding gene Chr7:137200350-137203276 (-)
LP/J ENSMUSG00230038093
 protein coding gene Chr7:138293680-138296612 (-)
NOD/ShiLtJ ENSMUSG00190019516
 protein coding gene Chr7:127959083-127962015 (-)
NZO/HlLtJ ENSMUSG00225050022
 protein coding gene Chr7:136502897-136505829 (-)
PWK/PhJ ENSLUMG00010035295
 protein coding gene Chr7:126347693-126350618 (-)
SPRET/EiJ no annotation
WSB/EiJ ENSIUOG00005030881
 protein coding gene Chr7:128646719-128649650 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    843
  • Tissues
    140
  • cDNA Data
    14
  • Literature Summary
    26
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 17703 NCBI Gene Model | MGI Sequence Detail 2932 C57BL/6J ±  kb
    transcript NM_001347609 RefSeq | MGI Sequence Detail 2355 ZRU/MplStud  
    polypeptide P70354 UniProt | EBI | MGI Sequence Detail 204 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 23
      Genomic 5
      cDNA 14
      Primer pair 2
      Other 2

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGD-MRK-35043, MGI:2141906
    References
    more
    • Summaries
      All 69
      Developmental Gene Expression 26
      Gene Ontology 7
      Phenotypes 10
    • Earliest
      J:11121 Holland PW, Cloning and evolutionary analysis of msh-like homeobox genes from mouse, zebrafish and ascidian. Gene. 1991 Feb 15;98(2):253-7
    • Latest
      J:348280 Gupta I, et al., Msx genes delineate a novel molecular map of the developing cerebellar neuroepithelium. Front Mol Neurosci. 2024;17:1356544
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory