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Etfb Gene Detail
Summary
  • Symbol
    Etfb
  • Name
    electron transferring flavoprotein, beta polypeptide
  • Synonyms
    0610009I16Rik, 2810441H06Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:106098
    NCBI Gene: 110826
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr7:43093507-43107224 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 28.25 cM, cytoband B2
  • Mapping Data
    11 experiments
Strain
Comparison
more
  • SNPs within 2kb
    207 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_106098
protein coding gene Chr7:43093496-43107224 (+)
129S1/SvImJ MGP_129S1SvImJ_G0032125
protein coding gene Chr7:43458024-43471590 (+)
A/J MGP_AJ_G0032110
protein coding gene Chr7:42571016-42584589 (+)
AKR/J MGP_AKRJ_G0032040
protein coding gene Chr7:43940781-43954349 (+)
BALB/cJ MGP_BALBcJ_G0032115
protein coding gene Chr7:42685786-42699478 (+)
C3H/HeJ MGP_C3HHeJ_G0031831
protein coding gene Chr7:44440327-44455165 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032599
protein coding gene Chr7:45651755-45666978 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029622
protein coding gene Chr7:44692686-44706156 (+)
CAST/EiJ MGP_CASTEiJ_G0031161
protein coding gene Chr7:35615307-35630344 (+)
CBA/J MGP_CBAJ_G0031800
protein coding gene Chr7:47096267-47110090 (+)
DBA/2J MGP_DBA2J_G0031949
protein coding gene Chr7:42370773-42384559 (+)
FVB/NJ MGP_FVBNJ_G0031910
protein coding gene Chr7:42090550-42104118 (+)
LP/J MGP_LPJ_G0032028
protein coding gene Chr7:44196718-44210215 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031946
protein coding gene Chr7:46046938-46062897 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032619
protein coding gene Chr7:43069746-43083514 (+)
PWK/PhJ MGP_PWKPhJ_G0030882
protein coding gene Chr7:35813343-35828092 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030721
protein coding gene Chr7:31120180-31133361 (+)
WSB/EiJ MGP_WSBEiJ_G0031275
protein coding gene Chr7:43612555-43626217 (+)



Homology
more
  • Human Ortholog
    ETFB, electron transfer flavoprotein subunit beta
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ETFB, electron transfer flavoprotein subunit beta
  • Synonyms
    FP585, MADD
  • Links
    NCBI Gene ID: 2109
    neXtProt AC: NX_P38117
    UniProt: P38117

  • Chr Location
    19q13.41; chr19:51345155-51366418 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human ETFB associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000004610 Ensembl Gene Model | MGI Sequence Detail 13718 C57BL/6J ±  kb
transcript ENSMUST00000004729 Ensembl | MGI Sequence Detail 893 Not Applicable  
polypeptide ENSMUSP00000004729 Ensembl | MGI Sequence Detail 255 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000007216 electron transfer flavoprotein subunit beta
  • InterPro Domains
    IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal
    IPR012255 Electron transfer flavoprotein, beta subunit
    IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site
    IPR033948 Electron transfer flavoprotein, beta subunit, N-terminal
    IPR014729 Rossmann-like alpha/beta/alpha sandwich fold
Molecular
Reagents
less
  • All nucleic 14
    cDNA 14

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-33785, MGI:1915610, MGI:1920006
References
more
  • Summaries
    All 43
    Developmental Gene Expression 3
    Gene Ontology 8
    Phenotypes 2
  • Earliest
    J:320288 Finocchiaro G, et al., cDNA cloning and mitochondrial import of the beta-subunit of the human electron-transfer flavoprotein. Eur J Biochem. 1993 May 1;213(3):1003-8
  • Latest
    J:285347 Zhang X, et al., Hepatic neddylation targets and stabilizes electron transfer flavoproteins to facilitate fatty acid beta-oxidation. Proc Natl Acad Sci U S A. 2020 Feb 4;117(5):2473-2483

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
03/21/2023
MGI 6.22
The Jackson Laboratory