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Nudc Gene Detail
Summary
  • Symbol
    Nudc
  • Name
    nudC nuclear distribution protein
  • Synonyms
    NudC, Silg92
  • Feature Type
    protein coding gene
  • IDs
    MGI:106014
    NCBI Gene: 18221
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:133259853-133273307 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 66.25 cM, cytoband D3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    227 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_106014
 protein coding gene Chr4:133259853-133273338 (-)
129S1/SvImJ no annotation
A/J MGP_AJ_G0028856
 protein coding gene Chr4:130109657-130123108 (-)
AKR/J MGP_AKRJ_G0028809
 protein coding gene Chr4:133808234-133821645 (-)
BALB/cJ MGP_BALBcJ_G0028879
 protein coding gene Chr4:130741147-130754962 (-)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0029321
 protein coding gene Chr4:140668715-140682165 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026592
 protein coding gene Chr4:123179287-123193159 (-)
CAST/EiJ MGP_CASTEiJ_G0028026
 protein coding gene Chr4:132174463-132188489 (-)
CBA/J MGP_CBAJ_G0028559
 protein coding gene Chr4:144356362-144369705 (-)
DBA/2J MGP_DBA2J_G0028708
 protein coding gene Chr4:130528379-130541703 (-)
FVB/NJ MGP_FVBNJ_G0028675
 protein coding gene Chr4:129405479-129420892 (-)
LP/J MGP_LPJ_G0028809
 protein coding gene Chr4:135908580-135924866 (-)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0029359
 protein coding gene Chr4:134232375-134245831 (-)
PWK/PhJ MGP_PWKPhJ_G0027747
 protein coding gene Chr4:127246539-127260571 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027573
 protein coding gene Chr4:130062315-130075774 (-)
WSB/EiJ MGP_WSBEiJ_G0028106
 protein coding gene Chr4:134408856-134424259 (-)



Homology
more
  • Human Ortholog
    NUDC, nuclear distribution C, dynein complex regulator
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NUDC, nuclear distribution C, dynein complex regulator
  • Synonyms
    HNUDC, MNUDC, NPD011
  • Links
    NCBI Gene ID: 10726
    neXtProt AC: NX_Q9Y266
    UniProt: Q9Y266

  • Chr Location
    1p36.11; chr1:26900161-26946871 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
  • All Mutations and Alleles
    40
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    2
  • Gene trapped
    32
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    4 involving Nudc
  • Find Mice (IMSR)
    18 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    799
  • Tissues
    93
  • cDNA Data
    14
  • Literature Summary
    4
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000028851 Ensembl Gene Model | MGI Sequence Detail 13455 C57BL/6J ±  kb
transcript ENSMUST00000030665 Ensembl | MGI Sequence Detail 1316 Not Applicable  
polypeptide ENSMUSP00000030665 Ensembl | MGI Sequence Detail 332 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 14
    Other 2

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-33696
References
more
  • Summaries
    All 44
    Developmental Gene Expression 4
    Gene Ontology 8
    Phenotypes 11
  • Earliest
    J:22945 Mixter PF, et al., Decreased CD4-CD8- TCR-alpha beta + cells in lpr/lpr mice lacking beta 2-microglobulin. J Immunol. 1995 Mar 1;154(5):2063-74
  • Latest
    J:197131 Lanctot AA, et al., Spatially dependent dynamic MAPK modulation by the nde1-lis1-brap complex patterns Mammalian CNS. Dev Cell. 2013 May 13;25(3):241-55
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/19/2023
MGI 6.22 		The Jackson Laboratory