mt-Ta MGI Mouse Gene Detail - MGI:102491 - mitochondrially encoded tRNA alanine

Symbol

mt-Ta
Name

mitochondrially encoded tRNA alanine
Synonyms

tRNA, tRNA-Ala, TrnA tRNA

Feature Type

tRNA gene
IDs

MGI:102491
NCBI Gene: 17726
Alliance

gene page
Transcription Start Sites

1 TSS

Sequence Map

ChrMT:5018-5086 bp, - strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome MT, Syntenic

SNPs within 2kb

21 from dbSNP Build 142
Strain Annotations

17

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_102491	tRNA gene	ChrMT:5018-5086 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0000315	tRNA gene	Chr9:126129685-126129753 (+)
A/J	MGP_AJ_G0000287	tRNA gene	Chr9:121301559-121301627 (+)
AKR/J	MGP_AKRJ_G0000276	tRNA gene	Chr9:124561080-124561148 (+)
BALB/cJ	MGP_BALBcJ_G0000281	tRNA gene	Chr9:121227002-121227070 (+)
C3H/HeJ	MGP_C3HHeJ_G0000268	tRNA gene	Chr9:125002365-125002433 (+)
C57BL/6NJ	no annotation
CAROLI/EiJ	MGP_CAROLIEiJ_G0000161	tRNA gene	Chr9:118446264-118446332 (+)
CAST/EiJ	MGP_CASTEiJ_G0000261	tRNA gene	Chr9:125036804-125036872 (+)
CBA/J	MGP_CBAJ_G0000262	tRNA gene	Chr9:134328486-134328554 (+)
DBA/2J	MGP_DBA2J_G0000264	tRNA gene	Chr9:120754998-120755066 (+)
FVB/NJ	MGP_FVBNJ_G0000276	tRNA gene	Chr9:119662426-119662494 (+)
LP/J	MGP_LPJ_G0000320	tRNA gene	Chr9:126465552-126465620 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0000280	tRNA gene	Chr9:135177309-135177377 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0000389	tRNA gene	Chr9:125026282-125026350 (+)
PWK/PhJ	MGP_PWKPhJ_G0000218	tRNA gene	Chr9:121209356-121209424 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0000201	tRNA gene	Chr9:125126596-125126664 (+)
WSB/EiJ	MGP_WSBEiJ_G0000267	tRNA gene	Chr9:124864759-124864827 (+)

Human Ortholog

TRNA, tRNA-Ala

Vertebrate Orthologs

1

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

TRNA, tRNA-Ala
Synonyms

MTTA
Links

HGNC:7475

NCBI Gene ID: 4553
Chr Location

chrMT:5587-5655 (-) GRCh38

MGI Vertebrate Homology

mt-Ta stringent orthology
1 human;1 mouse
HCOP

vertebrate homology predictions: TRNA
Gene Tree

mt-Ta

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Mutations/Alleles

1 with disease annotations

References

1 with disease annotations

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Phenotype Summary

9 phenotypes from multigenic genotypes
10 phenotype references

All Mutations and Alleles

2
Spontaneous

2
Find Mice (IMSR)

0 strains or lines available

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All GO Annotations

2
GO References

1

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706

Tissue x Stage Matrix

Other Mouse Links

Expression Atlas

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All Sequences

70

Ensembl

ENSMUSG00000064347 (Evidence)
NCBI Gene

17726

Representative Sequences				Length	Strain/Species	Flank
	genomic	17726	NCBI Gene Model \| MGI Sequence Detail	69	C57BL/6J	± kb

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All nucleic 52

Other 52

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MGD-MRK-19328

Summaries

All 23

Diseases 1

Gene Ontology 1

Phenotypes 10
Earliest

J:22484 Bibb MJ, et al., Sequence and gene organization of mouse mitochondrial DNA. Cell. 1981 Oct;26(2 Pt 2):167-80
Latest

J:345168 Kremer LS, et al., A role for BCL2L13 and autophagy in germline purifying selection of mtDNA. PLoS Genet. 2023 Jan;19(1):e1010573

TSS for mt-Ta:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr160281	ChrMT:5039-5069 (-)	32 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23