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Rab3d Gene Detail
Summary
  • Symbol
    Rab3d
  • Name
    RAB3D, member RAS oncogene family
  • Synonyms
    C130057E11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:97844
    NCBI Gene: 19340
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:21818787-21829488 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 7.91 cM, cytoband A2-A3
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    401 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_97844
 protein coding gene Chr9:21818787-21829623 (-)
129S1/SvImJ ENSMUSG00200048459
 protein coding gene Chr9:18773032-18783733 (-)
A/J ENSMUSG00195033520
 protein coding gene Chr9:18609669-18620370 (-)
AKR/J ENSMUSG00220031233
 protein coding gene Chr9:18612097-18622798 (-)
BALB/cJ ENSMUSG00180039220
 protein coding gene Chr9:18743959-18754661 (-)
C3H/HeJ ENSMUSG00175036539
 protein coding gene Chr9:18706497-18717198 (-)
C57BL/6NJ ENSMUSG00215035840
 protein coding gene Chr9:18703793-18714494 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031885
 protein coding gene Chr9:17910477-17922532 (-)
CAST/EiJ ENSTCUG00005030284
 protein coding gene Chr9:18747773-18759311 (-)
CBA/J ENSMUSG00210036316
 protein coding gene Chr9:18687426-18698127 (-)
DBA/2J ENSMUSG00185024477
 protein coding gene Chr9:18802730-18813431 (-)
FVB/NJ ENSMUSG00205033172
 protein coding gene Chr9:19038449-19049156 (-)
JF1/MsJ ENSUMUG00000043105
 protein coding gene Chr9:18902136-18913806 (-)
LP/J ENSMUSG00230037664
 protein coding gene Chr9:19197650-19208356 (-)
NOD/ShiLtJ ENSMUSG00190030650
 protein coding gene Chr9:18731422-18742128 (-)
NZO/HlLtJ ENSMUSG00225047773
 protein coding gene Chr9:19144698-19155399 (-)
PWK/PhJ ENSLUMG00010038647
 protein coding gene Chr9:18793047-18804742 (-)
SPRET/EiJ ENSMSPG00010018533
 protein coding gene Chr9:19022260-19033338 (-)
WSB/EiJ ENSIUOG00005043992
 protein coding gene Chr9:18273345-18284052 (-)



Homology
more
  • Human Ortholog
    RAB3D, RAB3D, member RAS oncogene family
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RAB3D, RAB3D, member RAS oncogene family
  • Synonyms
    D2-2, GOV, RAB16, RAD3D
  • Links
    NCBI Gene ID: 9545
    UniProt: O95716

  • Chr Location
    19p13.2; chr19:11322068-11346270 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    13 phenotypes from multigenic genotypes
    17 phenotype references
Mice homozygous for disruptions in this gene show no obvious phenotypic changes. Secretory granules in mast cells and some exocrine glands are double in volume.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    34
  • GO References
    16
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    680
  • Tissues
    12
  • cDNA Data
    149
  • Literature Summary
    6
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000019066 Ensembl Gene Model | MGI Sequence Detail 10702 C57BL/6J ±  kb
transcript ENSMUST00000115351 Ensembl | MGI Sequence Detail 3835 Not Applicable  
polypeptide ENSMUSP00000111008 Ensembl | MGI Sequence Detail 219 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 152
    Genomic 1
    cDNA 150
    Primer pair 1
    Antibodies 1

    Microarray probesets 7
Other
Accession IDs
less
MGD-MRK-13747, MGI:2442160
References
more
  • Summaries
    All 74
    Developmental Gene Expression 6
    Gene Ontology 16
    Phenotypes 17
  • Earliest
    J:1134 Baldini G, et al., Cloning of a Rab3 isotype predominantly expressed in adipocytes. Proc Natl Acad Sci U S A. 1992 Jun 1;89(11):5049-52
  • Latest
    J:319780 Yu Z, et al., Cathepsin S is a novel target for age-related dry eye. Exp Eye Res. 2022 Jan;214:108895
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory