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Prim2 Gene Detail
Summary
  • Symbol
    Prim2
  • Name
    DNA primase, p58 subunit
  • Feature Type
    protein coding gene
  • IDs
    MGI:97758
    NCBI Gene: 19076
  • Alliance
    genome feature page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:33492889-33708867 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 12.70 cM, cytoband B
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    6217 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_97758
 protein coding gene Chr1:33492889-33708876 (-)
129S1/SvImJ ENSMUSG00200003555
 protein coding gene Chr1:31021589-31249516 (-)
A/J ENSMUSG00195038765
 protein coding gene Chr1:30709283-30925028 (-)
AKR/J ENSMUSG00220008409
 protein coding gene Chr1:30730657-30946870 (-)
BALB/cJ ENSMUSG00180011301
 protein coding gene Chr1:30805837-31033823 (-)
C3H/HeJ ENSMUSG00175001025
 protein coding gene Chr1:30713606-30929347 (-)
C57BL/6NJ ENSMUSG00215024309
 protein coding gene Chr1:30795154-31011188 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014014
 protein coding gene Chr1:28223876-28437805 (-)
CAST/EiJ ENSTCUG00005002752
 protein coding gene Chr1:30851743-31069481 (-)
CBA/J ENSMUSG00210005722
 protein coding gene Chr1:30557118-30773297 (-)
DBA/2J ENSMUSG00185009913
 protein coding gene Chr1:31622794-31838529 (-)
FVB/NJ ENSMUSG00205033806
 protein coding gene Chr1:30739050-30954797 (-)
JF1/MsJ ENSUMUG00000022621
 protein coding gene Chr1:30819484-31052390 (-)
LP/J ENSMUSG00230021950
 protein coding gene Chr1:31663805-31891720 (-)
NOD/ShiLtJ ENSMUSG00190033278
 protein coding gene Chr1:30728186-30940235 (-)
NZO/HlLtJ ENSMUSG00225013458
 protein coding gene Chr1:34943413-35159151 (-)
PWK/PhJ ENSLUMG00010032816
 protein coding gene Chr1:30406731-30631928 (-)
SPRET/EiJ ENSMSPG00010027858
 protein coding gene Chr1:31801111-32014215 (-)
WSB/EiJ ENSIUOG00005035054
 protein coding gene Chr1:30712195-30930784 (-)



Homology
more
  • Human Ortholog
    PRIM2, DNA primase subunit 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PRIM2, DNA primase subunit 2
  • Synonyms
    p58, PRIM2A
  • Links
    NCBI Gene ID: 5558
    UniProt: P49643

  • Chr Location
    6p11.2; chr6:57221540-57646855 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    28
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    942
  • Tissues
    111
  • cDNA Data
    13
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 19076 NCBI Gene Model | MGI Sequence Detail 215979 C57BL/6J ±  kb
transcript NM_008922 RefSeq | MGI Sequence Detail 1966 ZRU/MplStud  
polypeptide P33610 UniProt | EBI | MGI Sequence Detail 505 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000013216 DNA primase large subunit
    (term hierarchy)
  • InterPro Domains
    IPR058560 DNA primase, large subunit C-terminal domain, eukaryotic and archaeal
    IPR016558 DNA primase, large subunit, eukaryotic
    IPR007238 DNA primase large subunit, eukaryotic/archaeal
Molecular
Reagents
less
  • All nucleic 14
    cDNA 13
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-13609, MGI:2138206
References
more
  • Summaries
    All 45
    Developmental Gene Expression 4
    Gene Ontology 8
    Phenotypes 10
  • Earliest
    J:22339 Prussak CE, et al., Mouse primase p49 subunit molecular cloning indicates conserved and divergent regions. J Biol Chem. 1989 Mar 25;264(9):4957-63
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory