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Nktr Gene Detail
Summary
  • Symbol
    Nktr
  • Name
    natural killer tumor recognition sequence
  • Synonyms
    5330401F18Rik, D9Wsu172e
  • Feature Type
    protein coding gene
  • IDs
    MGI:97346
    NCBI Gene: 18087
  • Alliance
    genome feature page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:121548235-121585909 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 72.57 cM
  • Mapping Data
    8 experiments
Strain
Comparison
more
  • SNPs within 2kb
    701 from dbSNP Build 142
  • Strain Annotations
    19
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_97346
 protein coding gene Chr9:121542244-121585909 (+)
129S1/SvImJ ENSMUSG00200028890
 protein coding gene Chr9:118669071-118707950 (+)
A/J ENSMUSG00195027250
 protein coding gene Chr9:117832097-117870940 (+)
AKR/J ENSMUSG00220018560
 protein coding gene Chr9:118286357-118325468 (+)
BALB/cJ ENSMUSG00180025778
 protein coding gene Chr9:118369112-118407995 (+)
C3H/HeJ ENSMUSG00175017967
 protein coding gene Chr9:118612543-118650513 (+)
C57BL/6NJ ENSMUSG00215031147
 protein coding gene Chr9:118501425-118540662 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032829
 protein coding gene Chr9:117086825-117124132 (+)
CAST/EiJ ENSTCUG00005016177
 protein coding gene Chr9:118209124-118247381 (+)
CBA/J ENSMUSG00210036773
 protein coding gene Chr9:118325149-118364260 (+)
DBA/2J ENSMUSG00185014112
 protein coding gene Chr9:118659363-118698473 (+)
FVB/NJ ENSMUSG00205024516
 protein coding gene Chr9:118500839-118539720 (+)
JF1/MsJ ENSUMUG00000040492
 protein coding gene Chr9:118489007-118527630 (+)
LP/J ENSMUSG00230033494
 protein coding gene Chr9:118808184-118847063 (+)
NOD/ShiLtJ ENSMUSG00190014660
 protein coding gene Chr9:118265393-118304271 (+)
NZO/HlLtJ ENSMUSG00225022345
 protein coding gene Chr9:119072454-119111691 (+)
PWK/PhJ ENSLUMG00010029762
 protein coding gene Chr9:118376643-118415276 (+)
SPRET/EiJ ENSMSPG00010020098
 protein coding gene Chr9:120082413-120119918 (+)
WSB/EiJ ENSIUOG00005018292
 protein coding gene Chr9:117692531-117731361 (+)



Homology
more
  • Human Ortholog
    NKTR, natural killer cell triggering receptor
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NKTR, natural killer cell triggering receptor
  • Synonyms
    CypNK, p104
  • Links
    NCBI Gene ID: 4820
    UniProt: P30414

  • Chr Location
    3p22.1; chr3:42600471-42648738 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    603
  • Tissues
    2
  • cDNA Data
    10
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032525 Ensembl Gene Model | MGI Sequence Detail 37675 C57BL/6J ±  kb
transcript ENSMUST00000035112 Ensembl | MGI Sequence Detail 7022 Not Applicable  
polypeptide ENSMUSP00000035112 Ensembl | MGI Sequence Detail 1453 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    10 Sequences
  • Protein Ontology
    PR:000011238 NK-tumor recognition protein
    (term hierarchy)
  • EC
    5.2.1.8
  • InterPro Domains
    IPR029000 Cyclophilin-like domain superfamily
    IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site
    IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain
  • GlyGen
    P30415 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 14
    Genomic 1
    cDNA 12
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-12886, MGD-MRK-36455, MGI:107878, MGI:2441695
References
more
  • Summaries
    All 47
    Developmental Gene Expression 1
    Gene Ontology 9
    Phenotypes 6
  • Earliest
    J:4951 Young HA, et al., Localization of a novel natural killer triggering receptor locus to human chromosome 3p23-p21 and mouse chromosome 9. Genomics. 1993 May;16(2):548-9
  • Latest
    J:380242 Arratia LM, et al., Experimental and computational evidence that Calpain-10 binds to the carboxy terminus of Na(V)1.2 and Na(V)1.6. Sci Rep. 2024 Mar 21;14(1):6761
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory