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H13 Gene Detail
Summary
  • Symbol
    H13
  • Name
    histocompatibility 13
  • Synonyms
    1200006O09Rik, 4930443L17Rik, 5031424B04Rik, H-13, Hm13, Spp
  • Feature Type
    protein coding gene
  • IDs
    MGI:95886
    NCBI Gene: 14950
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:152511381-152550590 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 75.41 cM
  • Mapping Data
    10 experiments
Strain
Comparison
more
  • SNPs within 2kb
    945 from dbSNP Build 142
  • Strain Annotations
    19
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_95886
 protein coding gene Chr2:152511292-152550590 (+)
129S1/SvImJ ENSMUSG00200026354
 protein coding gene Chr2:149428040-149467162 (+)
A/J ENSMUSG00195020484
 protein coding gene Chr2:149698432-149737646 (+)
AKR/J ENSMUSG00220038832
 protein coding gene Chr2:149020118-149059328 (+)
BALB/cJ ENSMUSG00180042722
 protein coding gene Chr2:149186296-149225425 (+)
C3H/HeJ ENSMUSG00175039526
 protein coding gene Chr2:149932521-149971648 (+)
C57BL/6NJ ENSMUSG00215020026
 protein coding gene Chr2:149354769-149393983 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024469
 protein coding gene Chr2:144554131-144593133 (+)
CAST/EiJ ENSTCUG00005038825
 protein coding gene Chr2:148280684-148319890 (+)
CBA/J ENSMUSG00210037406
 protein coding gene Chr2:149869039-149908168 (+)
DBA/2J ENSMUSG00185046360
 protein coding gene Chr2:149519280-149558436 (+)
FVB/NJ ENSMUSG00205020001
 protein coding gene Chr2:148616069-148655224 (+)
JF1/MsJ ENSUMUG00000021521
 protein coding gene Chr2:149187058-149226266 (+)
LP/J ENSMUSG00230035137
 protein coding gene Chr2:151176482-151215602 (+)
NOD/ShiLtJ ENSMUSG00190030423
 protein coding gene Chr2:149286423-149325626 (+)
NZO/HlLtJ ENSMUSG00225003108
 protein coding gene Chr2:159207408-159246552 (+)
PWK/PhJ ENSLUMG00010035439
 protein coding gene Chr2:149153646-149192770 (+)
SPRET/EiJ ENSMSPG00010026801
 protein coding gene Chr2:151881944-151918098 (+)
WSB/EiJ ENSIUOG00005046491
 protein coding gene Chr2:149023177-149062299 (+)



Homology
more
  • Human Ortholog
    HM13, histocompatibility minor 13
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    HM13, histocompatibility minor 13
  • Synonyms
    H13, HM13-IT1, IMP1, IMPAS, IMPAS-1, MSTP086, PSENL3, PSL3, SPP, SPPL1
  • Links
    NCBI Gene ID: 81502
    UniProt: Q8TCT9

  • Chr Location
    20q11.21; chr20:31514370-31577923 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    89 phenotypes from 1 allele in 1 genetic background
    20 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
This is one of several loci identified by development of congenic strains differing in resistance to transplantable tumors. C57BL/10 carries the a allele and B10.129(14M) carries the b allele.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    49
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    861
  • Tissues
    105
  • cDNA Data
    181
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000019188 Ensembl Gene Model | MGI Sequence Detail 39210 C57BL/6J ±  kb
    transcript ENSMUST00000089059 Ensembl | MGI Sequence Detail 1743 Not Applicable  
    polypeptide ENSMUSP00000086460 Ensembl | MGI Sequence Detail 394 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 191
      cDNA 182
      Primer pair 8
      Other 1

      Microarray probesets 10
    Other
    Accession IDs
    less
    MGD-MRK-10359, MGD-MRK-10481, MGI:1914866, MGI:1915400, MGI:2139237, MGI:2447815
    References
    more
    • Summaries
      All 73
      Developmental Gene Expression 4
      Gene Ontology 9
      Phenotypes 20
    • Earliest
      J:5026 Graff RJ, et al., Histocompatibility genes of mice. VI. Allografts in mice congenic at various non-H-2 histocompatibility loci. Transplantation. 1966 Jul;4(4):425-37
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory