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Rab12 Gene Detail
Summary
  • Symbol
    Rab12
  • Name
    RAB12, member RAS oncogene family
  • Synonyms
    2900054P15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:894284
    NCBI Gene: 19328
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:66801507-66826712 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 37.88 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    821 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_894284
 protein coding gene Chr17:66801507-66826724 (-)
129S1/SvImJ ENSMUSG00200037964
 protein coding gene Chr17:62142230-62167452 (-)
A/J ENSMUSG00195017752
 protein coding gene Chr17:63484540-63509761 (-)
AKR/J ENSMUSG00220017856
 protein coding gene Chr17:62564866-62590081 (-)
BALB/cJ ENSMUSG00180019509
 protein coding gene Chr17:63221858-63247078 (-)
C3H/HeJ ENSMUSG00175027499
 protein coding gene Chr17:62529369-62554591 (-)
C57BL/6NJ ENSMUSG00215017244
 protein coding gene Chr17:62189746-62214964 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021839
 protein coding gene Chr17:62640438-62665819 (-)
CAST/EiJ ENSTCUG00005026140
 protein coding gene Chr17:63146795-63171696 (-)
CBA/J ENSMUSG00210029594
 protein coding gene Chr17:62329290-62354510 (-)
DBA/2J ENSMUSG00185022553
 protein coding gene Chr17:65173764-65198984 (-)
FVB/NJ ENSMUSG00205012248
 protein coding gene Chr17:62948349-62973569 (-)
JF1/MsJ ENSUMUG00000038444
 protein coding gene Chr17:64828387-64853314 (-)
LP/J ENSMUSG00230014920
 protein coding gene Chr17:66160472-66185691 (-)
NOD/ShiLtJ ENSMUSG00190035060
 protein coding gene Chr17:62308209-62333434 (-)
NZO/HlLtJ ENSMUSG00225025627
 protein coding gene Chr17:68437212-68462431 (-)
PWK/PhJ ENSLUMG00010028620
 protein coding gene Chr17:62116921-62142301 (-)
SPRET/EiJ ENSMSPG00010015203
 protein coding gene Chr17:62472331-62498171 (-)
WSB/EiJ ENSIUOG00005031006
 protein coding gene Chr17:63181668-63206828 (-)



Homology
more
  • Human Ortholog
    RAB12, RAB12, member RAS oncogene family
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RAB12, RAB12, member RAS oncogene family
  • Links
    NCBI Gene ID: 201475
    UniProt: Q6IQ22

  • Chr Location
    18p11.22; chr18:8609437-8639383 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    30
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    69
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 19328 NCBI Gene Model | MGI Sequence Detail 25206 C57BL/6J ±  kb
transcript NM_024448 RefSeq | MGI Sequence Detail 2098 C57BL/6  
polypeptide P35283 UniProt | EBI | MGI Sequence Detail 291 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 69
    cDNA 69

    Microarray probesets 3
Other
Accession IDs
less
MGI:1920280, MGI:2147089, MGI:2147118
References
more
  • Summaries
    All 54
    Gene Ontology 11
    Phenotypes 12
  • Earliest
    J:24144 Chavrier P, et al., The complexity of the Rab and Rho GTP-binding protein subfamilies revealed by a PCR cloning approach. Gene. 1992 Mar 15;112(2):261-4
  • Latest
    J:388228 Li X, et al., Disruption of the LRRK2 substrate RAB12 facilitates neurotransmission and causes hyperactivity in mice. NPJ Parkinsons Dis. 2026 Apr 24;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory