About   Help   FAQ
Gngt2 Gene Detail
Summary
  • Symbol
    Gngt2
  • Name
    guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:893584
    NCBI Gene: 14710
  • Alliance
    genome feature page
  • Transcription Start Sites
    15 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:95733045-95736557 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 59.01 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    213 from dbSNP Build 142
  • Strain Annotations
    19
  • PCR
    1
  • RFLP
    2
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_893584
 protein coding gene Chr11:95728042-95736560 (+)
129S1/SvImJ ENSMUSG00200052790
 protein coding gene Chr11:92972394-92980913 (+)
A/J ENSMUSG00195049208
 protein coding gene Chr11:92691884-92700397 (+)
AKR/J ENSMUSG00220044699
 protein coding gene Chr11:92950917-92959431 (+)
BALB/cJ ENSMUSG00180046023
 protein coding gene Chr11:92940932-92949466 (+)
C3H/HeJ ENSMUSG00175050957
 protein coding gene Chr11:92951238-92959750 (+)
C57BL/6NJ ENSMUSG00215053929
 protein coding gene Chr11:92545380-92553901 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017014
 protein coding gene Chr11:91582539-91590974 (+)
CAST/EiJ ENSTCUG00005016341
 protein coding gene Chr11:92399884-92408516 (+)
CBA/J ENSMUSG00210052109
 protein coding gene Chr11:92654520-92663031 (+)
DBA/2J ENSMUSG00185046709
 protein coding gene Chr11:93002972-93011562 (+)
FVB/NJ ENSMUSG00205038355
 protein coding gene Chr11:92859418-92867936 (+)
JF1/MsJ ENSUMUG00000049415
 protein coding gene Chr11:93306878-93315393 (+)
LP/J ENSMUSG00230050355
 protein coding gene Chr11:94055559-94064077 (+)
NOD/ShiLtJ ENSMUSG00190046269
 protein coding gene Chr11:93034659-93043193 (+)
NZO/HlLtJ ENSMUSG00225052251
 protein coding gene Chr11:96111236-96119826 (+)
PWK/PhJ ENSLUMG00010048267
 protein coding gene Chr11:92855351-92863954 (+)
SPRET/EiJ ENSMSPG00010048402
 protein coding gene Chr11:93350404-93353827 (+)
WSB/EiJ ENSIUOG00005046010
 protein coding gene Chr11:92803514-92812046 (+)



Homology
more
  • Human Ortholog
    GNGT2, G protein subunit gamma transducin 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GNGT2, G protein subunit gamma transducin 2
  • Synonyms
    G-GAMMA-8, G-GAMMA-C, GNG9, GNGT8, HG3I
  • Links
    NCBI Gene ID: 2793
    UniProt: O14610

  • Chr Location
    17q21.32; chr17:49202791-49210593 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    18 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    625
  • Tissues
    6
  • cDNA Data
    22
  • Literature Summary
    9
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 14710 NCBI Gene Model | MGI Sequence Detail 3513 C57BL/6J ±  kb
    transcript NM_001284393 RefSeq | MGI Sequence Detail 590 Not Specified  
    polypeptide Q61017 UniProt | EBI | MGI Sequence Detail 69 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • Protein Ontology
      PR:000008114 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
      (term hierarchy)
    • InterPro Domains
      IPR036284 G-protein gamma-like domain superfamily
      IPR001770 G-protein, gamma subunit
      IPR015898 G-protein, gamma subunit-like domain
    Molecular
    Reagents
    less
    • All nucleic 33
      Genomic 6
      cDNA 24
      Primer pair 3
      Antibodies 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2144460
    References
    more
    • Summaries
      All 54
      Developmental Gene Expression 9
      Gene Ontology 5
      Phenotypes 18
    • Earliest
      J:34526 Williams CJ, et al., G protein gene expression during mouse oocyte growth and maturation, and preimplantation embryo development. Mol Reprod Dev. 1996 Jul;44(3):315-23
    • Latest
      J:354849 Wutikeli H, et al., Role of Elavl-like RNA-binding protein in retinal development and signal transduction. Biochim Biophys Acta Mol Basis Dis. 2024 Sep 20;1871(1):167518
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory