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Cyp2f2 Gene Detail
Summary
  • Symbol
    Cyp2f2
  • Name
    cytochrome P450, family 2, subfamily f, polypeptide 2
  • Synonyms
    Cyp2f
  • Feature Type
    protein coding gene
  • IDs
    MGI:88608
    NCBI Gene: 13107
  • Alliance
  • Transcription Start Sites
    44 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:26819380-26833085 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 7, 15.82 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    419 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_88608
protein coding gene Chr7:26819334-26833085 (+)
129S1/SvImJ ENSMUSG00200041056
protein coding gene Chr7:16616291-16630039 (+)
A/J ENSMUSG00195049737
protein coding gene Chr7:19255857-19269589 (+)
AKR/J ENSMUSG00220044175
protein coding gene Chr7:25216382-25230111 (-)
BALB/cJ ENSMUSG00180052287
protein coding gene Chr7:17321049-17334780 (+)
C3H/HeJ ENSMUSG00175049451
protein coding gene Chr7:18377511-18391269 (+)
C57BL/6NJ ENSMUSG00215054655
protein coding gene Chr7:16508506-16522264 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029396
protein coding gene Chr7:26367315-26380774 (+)
CAST/EiJ ENSTCUG00005047148
protein coding gene Chr7:18312520-18326226 (+)
CBA/J ENSMUSG00210051590
protein coding gene Chr7:17563014-17576772 (+)
DBA/2J ENSMUSG00185050016
protein coding gene Chr7:20670370-20684125 (+)
FVB/NJ ENSMUSG00205049280
protein coding gene Chr7:17352187-17365944 (+)
JF1/MsJ ENSUMUG00000046554
protein coding gene Chr7:25089471-25103224 (+)
LP/J ENSMUSG00230053252
protein coding gene Chr7:25842269-25856021 (+)
NOD/ShiLtJ ENSMUSG00190032101
protein coding gene Chr7:17003608-17017307 (+)
NZO/HlLtJ ENSMUSG00225024289
protein coding gene Chr7:24719073-24732826 (+)
PWK/PhJ ENSLUMG00010035573
protein coding gene Chr7:17026251-17039833 (+)
SPRET/EiJ ENSMSPG00010050407
protein coding gene Chr7:16414824-16430846 (+)
WSB/EiJ ENSIUOG00005050791
protein coding gene Chr7:11261740-11275483 (+)



Homology
more
  • Human Ortholog
    CYP2F1, cytochrome P450 family 2 subfamily F member 1
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CYP2F1, cytochrome P450 family 2 subfamily F member 1
  • Synonyms
    C2F1, CYP2F, CYPIIF1
  • Links
    NCBI Gene ID: 1572
    UniProt: P24903

  • Chr Location
    19q13.2; chr19:41114432-41128381 (+)  GRCh38

  • Human Ortholog
    CYP2F2P, cytochrome P450 family 2 subfamily F member 2, pseudogene
  • Synonyms
    CYP2F1P
  • Links
    NCBI Gene ID: 171427

  • Chr Location
    19q13.2; chr19:40818477-40826773 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 2 alleles in 2 genetic backgrounds
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit resistance to napthalene-induced toxicity in the lungs.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 13107 NCBI Gene Model | MGI Sequence Detail 13706 C57BL/6J ±  kb
    transcript NM_007817 RefSeq | MGI Sequence Detail 1822 C57BL/6  
    polypeptide P33267 UniProt | EBI | MGI Sequence Detail 491 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 304
      cDNA 300
      Primer pair 3
      Other 1
      Antibodies 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGD-MRK-2328, MGD-MRK-2329
    References
    more
    • Summaries
      All 67
      Developmental Gene Expression 21
      Gene Ontology 7
      Phenotypes 15
    • Earliest
      J:10678 Nhamburo PT, et al., The human CYP2F gene subfamily: identification of a cDNA encoding a new cytochrome P450, cDNA-directed expression, and chromosome mapping. Biochemistry. 1990 Jun 12;29(23):5491-9
    • Latest
      J:387966 Marsal-Beltran A, et al., SUCNR1 coordinates metabolic flux, mitochondrial function, and nutrient-dependent adaptation in hepatocytes. Sci Adv. 2026 Jun 12;12(24):eaec8873

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    last database update
    09/08/2026
    MGI 6.24
    The Jackson Laboratory