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Dynlt1a Gene Detail
Summary
  • Symbol
    Dynlt1a
  • Name
    dynein light chain Tctex-type 1A
Location &
Maps
more
  • Sequence Map
    Chr17:6356619-6367749 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 3.88 cM
Strain
Comparison
more
  • SNPs within 2kb
    158 from dbSNP Build 142
  • Strain Annotations
    2
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3807506
 protein coding gene Chr17:6356615-6367775 (-)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ MGP_CAROLIEiJ_G0021032
 protein coding gene Chr17:3180031-3186525 (-)
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
JF1/MsJ no annotation
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    DYNLT1, dynein light chain Tctex-type 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DYNLT1, dynein light chain Tctex-type 1
  • Synonyms
    CW-1, TCTEL1, tctex-1, TCTEX1
  • Links
    NCBI Gene ID: 6993
    UniProt: P63172

  • Chr Location
    6q25.3; chr6:158636474-158644755 (-)  GRCh38
Human Diseases
less
  • References
    6 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    374 phenotype references
  • All Mutations and Alleles
    3
  • Endonuclease-mediated
    1
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    1 involving Dynlt1a
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    8 strains or lines available
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    3
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 100310872 NCBI Gene Model | MGI Sequence Detail 11131 C57BL/6J ±  kb
transcript NM_001166629 RefSeq | MGI Sequence Detail 4978 Not Specified  
polypeptide NP_001160101 RefSeq | MGI Sequence Detail 113 Not Specified  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3
References
more
  • Summaries
    All 383
    Developmental Gene Expression 1
    Diseases 6
    Phenotypes 374
  • Earliest
    J:30229 Davisson MT, et al., Segmental trisomy as a mouse model for Down syndrome. Prog Clin Biol Res. 1993;384:117-33
  • Latest
    J:391449 Thibodeau J, et al., Loss of cystathionine-beta-synthase contributes to elevated OXPHOS, a vulnerability in Ara-C-resistant Myeloid Leukemia in Down syndrome. Biochem Pharmacol. 2026 Feb 13;247:117815
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory