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Tmem233 Gene Detail
Summary
  • Symbol
    Tmem233
  • Name
    transmembrane protein 233
  • Synonyms
    Gm13843, Mcare
  • Feature Type
    protein coding gene
  • IDs
    MGI:3651514
    NCBI Gene: 545798
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:116176814-116221303 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 56.10 cM
Strain
Comparison
more
  • SNPs within 2kb
    1803 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3651514
 protein coding gene Chr5:116176807-116221326 (-)
129S1/SvImJ ENSMUSG00200021251
 protein coding gene Chr5:109917085-109961551 (-)
A/J ENSMUSG00195029802
 protein coding gene Chr5:109437351-109481904 (-)
AKR/J ENSMUSG00220051038
 protein coding gene Chr5:108946840-108991316 (-)
BALB/cJ ENSMUSG00180041414
 protein coding gene Chr5:109567867-109612340 (-)
C3H/HeJ ENSMUSG00175042722
 protein coding gene Chr5:111555694-111600171 (-)
C57BL/6NJ ENSMUSG00215033641
 protein coding gene Chr5:109578266-109622760 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027635
 protein coding gene Chr5:108992572-109038253 (-)
CAST/EiJ ENSTCUG00005031295
 protein coding gene Chr5:108759422-108803140 (-)
CBA/J ENSMUSG00210033000
 protein coding gene Chr5:110306734-110351224 (-)
DBA/2J ENSMUSG00185042102
 protein coding gene Chr5:113366100-113410566 (-)
FVB/NJ ENSMUSG00205049669
 protein coding gene Chr5:109206532-109251142 (-)
JF1/MsJ ENSUMUG00000052168
 protein coding gene Chr5:116189979-116235486 (-)
LP/J ENSMUSG00230047726
 protein coding gene Chr5:117455219-117499685 (-)
NOD/ShiLtJ ENSMUSG00190045860
 protein coding gene Chr5:109241894-109286445 (-)
NZO/HlLtJ ENSMUSG00225015359
 protein coding gene Chr5:125115508-125159967 (-)
PWK/PhJ ENSLUMG00010024404
 protein coding gene Chr5:108083338-108128703 (-)
SPRET/EiJ ENSMSPG00010037460
 protein coding gene Chr5:111377053-111419403 (-)
WSB/EiJ ENSIUOG00005040282
 protein coding gene Chr5:111947756-111992235 (-)



Homology
more
  • Human Ortholog
    TMEM233, transmembrane protein 233
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM233, transmembrane protein 233
  • Synonyms
    DSPB2, IFITMD2
  • Links
    NCBI Gene ID: 387890
    UniProt: B4DJY2

  • Chr Location
    12q24.23; chr12:119593774-119654295 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    16 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    599
  • Tissues
    1
  • cDNA Data
    1
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000079278 Ensembl Gene Model | MGI Sequence Detail 44490 C57BL/6J ±  kb
transcript ENSMUST00000111997 Ensembl | MGI Sequence Detail 2477 Not Applicable  
polypeptide ENSMUSP00000107628 Ensembl | MGI Sequence Detail 110 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 2
    cDNA 1
    Primer pair 1
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 16
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:378153 Sasaki T, et al., MCARE enhances SERCA1 activity in fast-twitch muscle to maintain calcium handling and muscle integrity. Nat Commun. 2025 Dec 10;17(1):629
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory