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Cldn25 Gene Detail
Summary
  • Symbol
    Cldn25
  • Name
    claudin 25
  • Synonyms
    Cldn21, Cldn21-ps, Cldn25, Cldn25-ps
Location &
Maps
more
  • Sequence Map
    Chr9:48958902-48959642 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 26.58 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    112 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3642767
 protein coding gene Chr9:48958857-48959642 (-)
129S1/SvImJ ENSMUSG00200019003
 pseudogene Chr9:46125324-46126016 (-)
A/J ENSMUSG00195024718
 pseudogene Chr9:45806906-45807598 (-)
AKR/J ENSMUSG00220043480
 pseudogene Chr9:45897888-45898580 (-)
BALB/cJ ENSMUSG00180033803
 pseudogene Chr9:45918273-45918965 (-)
C3H/HeJ ENSMUSG00175015679
 pseudogene Chr9:45930438-45931130 (-)
C57BL/6NJ ENSMUSG00215038351
 pseudogene Chr9:45882327-45883019 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0012394
 pseudogene Chr9:45920075-45920767 (-)
CAST/EiJ ENSTCUG00005016468
 pseudogene Chr9:45856398-45857090 (-)
CBA/J ENSMUSG00210016737
 pseudogene Chr9:46006797-46007489 (-)
DBA/2J ENSMUSG00185012057
 pseudogene Chr9:46044703-46045395 (-)
FVB/NJ ENSMUSG00205044018
 pseudogene Chr9:46280112-46280804 (-)
JF1/MsJ ENSUMUG00000044980
 pseudogene Chr9:46103259-46103951 (-)
LP/J ENSMUSG00230042266
 pseudogene Chr9:46341909-46342601 (-)
NOD/ShiLtJ ENSMUSG00190026973
 pseudogene Chr9:46131369-46132061 (-)
NZO/HlLtJ ENSMUSG00225045051
 pseudogene Chr9:46303413-46304105 (-)
PWK/PhJ ENSLUMG00010022542
 pseudogene Chr9:46067881-46068573 (-)
SPRET/EiJ ENSMSPG00010011470
 pseudogene Chr9:46838827-46839519 (-)
WSB/EiJ ENSIUOG00005022739
 pseudogene Chr9:45536381-45537073 (-)



Homology
more
  • Human Ortholog
    CLDN25, claudin 25
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CLDN25, claudin 25
  • Links
    NCBI Gene ID: 644672
    UniProt: C9JDP6

  • Chr Location
    11q23.2; chr11:113779796-113780485 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    624
  • Tissues
    20
  • cDNA Data
    1
  • Literature Summary
    1
Sequences &
Gene Models
less
  • All Sequences
    26
  • RefSeq
    2
  • UniProt
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000105298 Ensembl Gene Model | MGI Sequence Detail 741 C57BL/6J ±  kb
transcript ENSMUST00000197641 Ensembl | MGI Sequence Detail 741 Not Applicable  
polypeptide ENSMUSP00000160039 Ensembl | MGI Sequence Detail 230 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 3
    cDNA 1
    Primer pair 1
    Other 1
    Antibodies 1
Other
Accession IDs
less
MGI:6434312
References
more
  • Summaries
    All 14
    Developmental Gene Expression 1
    Gene Ontology 5
  • Earliest
    J:169091 Mineta K, et al., Predicted expansion of the claudin multigene family. FEBS Lett. 2011 Feb 18;585(4):606-12
  • Latest
    J:236202 Tanaka H, et al., Claudin-21 Has a Paracellular Channel Role at Tight Junctions. Mol Cell Biol. 2016 Jan 04;36(6):954-64
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory