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Wfdc13 Gene Detail
Summary
  • Symbol
    Wfdc13
  • Name
    WAP four-disulfide core domain 13
  • Feature Type
    protein coding gene
  • IDs
    MGI:3582777
    NCBI Gene: 408190
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:164527027-164529626 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 2, 85.25 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    249 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3582777
protein coding gene Chr2:164527027-164529626 (+)
129S1/SvImJ ENSMUSG00200016570
protein coding gene Chr2:161414070-161417248 (+)
A/J ENSMUSG00195023696
protein coding gene Chr2:161747179-161749778 (+)
AKR/J ENSMUSG00220013409
protein coding gene Chr2:161076687-161079290 (+)
BALB/cJ ENSMUSG00180048026
protein coding gene Chr2:161200919-161203518 (+)
C3H/HeJ ENSMUSG00175047032
protein coding gene Chr2:161949604-161952230 (+)
C57BL/6NJ ENSMUSG00215024199
protein coding gene Chr2:161398937-161401536 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024660
protein coding gene Chr2:156633033-156635815 (+)
CAST/EiJ ENSTCUG00005044014
protein coding gene Chr2:160317351-160320143 (+)
CBA/J ENSMUSG00210015574
protein coding gene Chr2:161881573-161884172 (+)
DBA/2J ENSMUSG00185044273
protein coding gene Chr2:161616789-161619414 (+)
FVB/NJ ENSMUSG00205025751
protein coding gene Chr2:160637641-160640280 (+)
JF1/MsJ ENSUMUG00000016802
protein coding gene Chr2:161259168-161262345 (+)
LP/J ENSMUSG00230039314
protein coding gene Chr2:163175190-163178362 (+)
NOD/ShiLtJ ENSMUSG00190028231
protein coding gene Chr2:161286407-161289006 (+)
NZO/HlLtJ ENSMUSG00225050488
protein coding gene Chr2:171179111-171181736 (+)
PWK/PhJ ENSLUMG00010045241
protein coding gene Chr2:161161641-161164792 (+)
SPRET/EiJ ENSMSPG00010025157
protein coding gene Chr2:163926583-163928756 (+)
WSB/EiJ ENSIUOG00005037726
protein coding gene Chr2:161007480-161010079 (+)



Homology
more
  • Human Ortholog
    WFDC13, WAP four-disulfide core domain 13
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    WFDC13, WAP four-disulfide core domain 13
  • Synonyms
    C20orf138, dJ601O1.3, WAP13
  • Links
    NCBI Gene ID: 164237
    UniProt: Q8IUB5

  • Chr Location
    20q13.12; chr20:45702038-45708817 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 408190 NCBI Gene Model | MGI Sequence Detail 2600 C57BL/6J ±  kb
transcript NM_001012704 RefSeq | MGI Sequence Detail 1074 C57BL/6  
polypeptide Q5DQQ6 UniProt | EBI | MGI Sequence Detail 81 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 3
    cDNA 3

    Microarray probesets 1
References
more
  • Summaries
    All 23
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:95646 Puente XS, et al., A genomic analysis of rat proteases and protease inhibitors. Genome Res. 2004 Apr;14(4):609-22
  • Latest
    J:300068 Andrade AD, et al., Lipopolysaccharide-induced epididymitis modifies the transcriptional profile of Wfdc genes in mice. Biol Reprod. 2021 Jan 4;104(1):144-158

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/08/2026
MGI 6.24
The Jackson Laboratory