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Ano7 Gene Detail
Summary
  • Symbol
    Ano7
  • Name
    anoctamin 7
  • Synonyms
    IPCA-5, NGEP, NGEP-L, Pcanap5, Tmem16g
  • Feature Type
    protein coding gene
  • IDs
    MGI:3052714
    NCBI Gene: 404545
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:93301652-93332025 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 47.24 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    860 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3052714
 protein coding gene Chr1:93301518-93332026 (+)
129S1/SvImJ ENSMUSG00200037761
 protein coding gene Chr1:90517862-90548296 (+)
A/J ENSMUSG00195031676
 protein coding gene Chr1:90076778-90107216 (+)
AKR/J ENSMUSG00220044126
 protein coding gene Chr1:90231508-90261942 (+)
BALB/cJ ENSMUSG00180015048
 protein coding gene Chr1:90393997-90424421 (+)
C3H/HeJ ENSMUSG00175001024
 protein coding gene Chr1:90271918-90302333 (+)
C57BL/6NJ ENSMUSG00215029972
 protein coding gene Chr1:90204170-90234549 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014455
 protein coding gene Chr1:85848012-85879583 (+)
CAST/EiJ ENSTCUG00005006854
 protein coding gene Chr1:89854704-89885123 (+)
CBA/J ENSMUSG00210012251
 protein coding gene Chr1:90117130-90147547 (+)
DBA/2J ENSMUSG00185013339
 protein coding gene Chr1:94590126-94620556 (+)
FVB/NJ ENSMUSG00205035586
 protein coding gene Chr1:89519713-89550151 (+)
JF1/MsJ ENSUMUG00000011154
 protein coding gene Chr1:93329763-93360305 (+)
LP/J ENSMUSG00230020875
 protein coding gene Chr1:93853963-93884393 (+)
NOD/ShiLtJ ENSMUSG00190022639
 protein coding gene Chr1:90161721-90192155 (+)
NZO/HlLtJ ENSMUSG00225002729
 protein coding gene Chr1:97753098-97783447 (+)
PWK/PhJ ENSLUMG00010040184
 protein coding gene Chr1:89717544-89748071 (+)
SPRET/EiJ ENSMSPG00010044874
 protein coding gene Chr1:91756313-91786166 (+)
WSB/EiJ ENSIUOG00005034833
 protein coding gene Chr1:89814286-89844619 (+)



Homology
more
  • Human Ortholog
    ANO7, anoctamin 7
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ANO7, anoctamin 7
  • Synonyms
    D-TMPP, DTMPP, IPCA-5, IPCA5, NGEP, PCANAP5, PCANAP5L, TMEM16G
  • Links
    NCBI Gene ID: 50636
    UniProt: Q6IWH7

  • Chr Location
    2q37.3; chr2:241188509-241240308 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    6
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000034107 Ensembl Gene Model | MGI Sequence Detail 30374 C57BL/6J ±  kb
    transcript ENSMUST00000186641 Ensembl | MGI Sequence Detail 3984 Not Applicable  
    polypeptide ENSMUSP00000140438 Ensembl | MGI Sequence Detail 859 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 6
      cDNA 6

      Microarray probesets 1
    References
    more
    • Summaries
      All 35
      Gene Ontology 9
      Phenotypes 10
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory