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Ubqln3 Gene Detail
Summary
  • Symbol
    Ubqln3
  • Name
    ubiquilin 3
  • Synonyms
    4933400K24Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3045291
    NCBI Gene: 244178
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:103789830-103792486 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 54.85 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    134 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3045291
 protein coding gene Chr7:103789828-103792528 (-)
129S1/SvImJ ENSMUSG00200043104
 protein coding gene Chr7:90648173-90650829 (-)
A/J ENSMUSG00195054208
 protein coding gene Chr7:95147918-95150574 (-)
AKR/J ENSMUSG00220049169
 protein coding gene Chr7:88519204-88521860 (-)
BALB/cJ ENSMUSG00180044475
 protein coding gene Chr7:91831024-91833680 (-)
C3H/HeJ ENSMUSG00175049478
 protein coding gene Chr7:92471582-92474238 (-)
C57BL/6NJ ENSMUSG00215051080
 protein coding gene Chr7:91637602-91640258 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030179
 protein coding gene Chr7:106636741-106639397 (-)
CAST/EiJ ENSTCUG00005052804
 protein coding gene Chr7:95043153-95045804 (-)
CBA/J ENSMUSG00210045842
 protein coding gene Chr7:92299008-92301664 (-)
DBA/2J ENSMUSG00185056791
 protein coding gene Chr7:96650589-96653245 (-)
FVB/NJ ENSMUSG00205029944
 protein coding gene Chr7:92283701-92286357 (-)
JF1/MsJ ENSUMUG00000026360
 protein coding gene Chr7:101617493-101620147 (-)
LP/J ENSMUSG00230041923
 protein coding gene Chr7:102752837-102755493 (-)
NOD/ShiLtJ ENSMUSG00190036698
 protein coding gene Chr7:92573465-92576119 (-)
NZO/HlLtJ ENSMUSG00225014953
 protein coding gene Chr7:100938056-100940712 (-)
PWK/PhJ ENSLUMG00010043505
 protein coding gene Chr7:90754928-90757581 (-)
SPRET/EiJ ENSMSPG00010033580
 protein coding gene Chr7:91964178-91966834 (-)
WSB/EiJ ENSIUOG00005048925
 protein coding gene Chr7:92876527-92879183 (-)



Homology
more
  • Human Ortholog
    UBQLN3, ubiquilin 3
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    UBQLN3, ubiquilin 3
  • Synonyms
    TUP-1
  • Links
    NCBI Gene ID: 50613
    UniProt: Q9H347

  • Chr Location
    11p15.4; chr11:5507300-5509958 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 2 alleles in 2 genetic backgrounds
    13 phenotype references
Mice homozygous for a knock-out allele are viable and developmentally normal with no apparent defects in male fertility or spermatogenesis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    604
  • Tissues
    1
  • cDNA Data
    6
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000051618 Ensembl Gene Model | MGI Sequence Detail 2657 C57BL/6J ±  kb
transcript ENSMUST00000057254 Ensembl | MGI Sequence Detail 2376 Not Applicable  
polypeptide ENSMUSP00000055229 Ensembl | MGI Sequence Detail 658 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 4
References
more
  • Summaries
    All 31
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 13
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:279039 Lu Y, et al., CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched genes dispensable for male fertility in mice. Biol Reprod. 2019 Aug 1;101(2):501-511
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory