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Hjurp Gene Detail
Summary
  • Symbol
    Hjurp
  • Name
    Holliday junction recognition protein
  • Synonyms
    6430706D22Rik, A730008H23Rik, C330011F01Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685821
    NCBI Gene: 381280
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:88190193-88205355 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 44.57 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    539 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685821
 protein coding gene Chr1:88186578-88205366 (-)
129S1/SvImJ ENSMUSG00200036788
 protein coding gene Chr1:85431911-85447072 (-)
A/J ENSMUSG00195028001
 protein coding gene Chr1:84992741-85007899 (-)
AKR/J ENSMUSG00220042816
 protein coding gene Chr1:85140629-85155790 (-)
BALB/cJ ENSMUSG00180014786
 protein coding gene Chr1:85279439-85294601 (-)
C3H/HeJ ENSMUSG00175001356
 protein coding gene Chr1:85158338-85173500 (-)
C57BL/6NJ ENSMUSG00215023174
 protein coding gene Chr1:85088996-85104158 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014398
 protein coding gene Chr1:80751309-80764704 (-)
CAST/EiJ ENSTCUG00005006561
 protein coding gene Chr1:84735830-84751001 (-)
CBA/J ENSMUSG00210012038
 protein coding gene Chr1:85003636-85018798 (-)
DBA/2J ENSMUSG00185015500
 protein coding gene Chr1:89476972-89492133 (-)
FVB/NJ ENSMUSG00205021918
 protein coding gene Chr1:84426407-84441568 (-)
JF1/MsJ ENSUMUG00000006223
 protein coding gene Chr1:88241901-88257054 (-)
LP/J ENSMUSG00230016362
 protein coding gene Chr1:88768217-88783378 (-)
NOD/ShiLtJ ENSMUSG00190028845
 protein coding gene Chr1:85067261-85082422 (-)
NZO/HlLtJ ENSMUSG00225001778
 protein coding gene Chr1:92664408-92679569 (-)
PWK/PhJ no annotation
SPRET/EiJ ENSMSPG00010044690
 protein coding gene Chr1:86660634-86675446 (-)
WSB/EiJ ENSIUOG00005039100
 protein coding gene Chr1:84692625-84706875 (-)



Homology
more
  • Human Ortholog
    HJURP, Holliday junction recognition protein
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    HJURP, Holliday junction recognition protein
  • Synonyms
    FAKTS, hFLEG1, URLC9
  • Links
    NCBI Gene ID: 55355
    UniProt: Q8NCD3

  • Chr Location
    2q37.1; chr2:233833416-233854566 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    635
  • Tissues
    19
  • cDNA Data
    18
  • Literature Summary
    7
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000044783 Ensembl Gene Model | MGI Sequence Detail 15163 C57BL/6J ±  kb
transcript ENSMUST00000054674 Ensembl | MGI Sequence Detail 4878 Not Applicable  
polypeptide ENSMUSP00000054263 Ensembl | MGI Sequence Detail 667 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    10 Sequences
  • Protein Ontology
    PR:000008607 Holliday junction recognition protein
    (term hierarchy)
  • InterPro Domains
    IPR018465 Centromere protein Scm3/HJURP
    IPR021052 Holliday junction recognition protein, HJURP, central domain
    IPR022102 Holliday junction regulator protein family C-terminal
  • GlyGen
    Q6PG16 1 site
Molecular
Reagents
less
  • All nucleic 21
    cDNA 20
    Primer pair 1

    Microarray probesets 8
Other
Accession IDs
less
MGI:1925855, MGI:3612871
References
more
  • Summaries
    All 43
    Developmental Gene Expression 7
    Gene Ontology 6
    Phenotypes 7
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory