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Lrrc10b Gene Detail
Summary
  • Symbol
    Lrrc10b
  • Name
    leucine rich repeat containing 10B
  • Synonyms
    Gm705, LOC278795, SerdinR
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685551
    NCBI Gene: 278795
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:10432735-10434811 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 6.60 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    119 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685551
 protein coding gene Chr19:10432735-10434837 (-)
129S1/SvImJ ENSMUSG00200049916
 protein coding gene Chr19:7111593-7113697 (-)
A/J ENSMUSG00195044524
 protein coding gene Chr19:7322809-7324919 (-)
AKR/J ENSMUSG00220046293
 protein coding gene Chr19:7232656-7234762 (-)
BALB/cJ ENSMUSG00180044491
 protein coding gene Chr19:7686817-7688925 (-)
C3H/HeJ ENSMUSG00175009228
 protein coding gene Chr19:6960459-6962561 (-)
C57BL/6NJ ENSMUSG00215044022
 protein coding gene Chr19:7028932-7031034 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022687
 protein coding gene Chr19:7682332-7684415 (-)
CAST/EiJ ENSTCUG00005040689
 protein coding gene Chr19:6827617-6829729 (-)
CBA/J ENSMUSG00210047549
 protein coding gene Chr19:7159058-7161160 (-)
DBA/2J ENSMUSG00185050813
 protein coding gene Chr19:7568772-7570872 (-)
FVB/NJ ENSMUSG00205050846
 protein coding gene Chr19:7050259-7052349 (-)
JF1/MsJ ENSUMUG00000055448
 protein coding gene Chr19:7687266-7689369 (-)
LP/J ENSMUSG00230053596
 protein coding gene Chr19:8486287-8488389 (-)
NOD/ShiLtJ ENSMUSG00190037530
 protein coding gene Chr19:6784404-6786510 (-)
NZO/HlLtJ ENSMUSG00225044976
 protein coding gene Chr19:12195132-12197234 (-)
PWK/PhJ ENSLUMG00010006161
 protein coding gene Chr19:7072601-7074713 (-)
SPRET/EiJ ENSMSPG00010045317
 protein coding gene Chr19:6912182-6914338 (-)
WSB/EiJ ENSIUOG00005048659
 protein coding gene Chr19:6676228-6678332 (-)



Homology
more
  • Human Ortholog
    LRRC10B, leucine rich repeat containing 10B
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LRRC10B, leucine rich repeat containing 10B
  • Links
    NCBI Gene ID: 390205
    UniProt: A6NIK2

  • Chr Location
    11q12.2; chr11:61508749-61511018 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    614
  • Tissues
    8
  • cDNA Data
    3
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 278795 NCBI Gene Model | MGI Sequence Detail 2077 C57BL/6J ±  kb
transcript NM_001111140 RefSeq | MGI Sequence Detail 2077 C57BL/6  
polypeptide NP_001104610 RefSeq | MGI Sequence Detail 292 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR001611 Leucine-rich repeat
    IPR050216 Leucine-rich repeat domain-containing protein
    IPR032675 Leucine-rich repeat domain superfamily
    IPR003591 Leucine-rich repeat, typical subtype
Molecular
Reagents
less
  • All nucleic 6
    cDNA 3
    Primer pair 3

    Microarray probesets 1
References
more
  • Summaries
    All 17
    Developmental Gene Expression 2
    Gene Ontology 1
    Phenotypes 2
  • Earliest
    J:98394 Adameyko II, et al., Expression and regulation of mouse SERDIN1, a highly conserved cardiac-specific leucine-rich repeat protein. Dev Dyn. 2005 Jun;233(2):540-52
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/15/2026
MGI 6.29 		The Jackson Laboratory