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Rtl9 Gene Detail
Summary
  • Symbol
    Rtl9
  • Name
    retrotransposon Gag like 9
  • Synonyms
    Mar9, Mart9, Rgag1
Location &
Maps
more
  • Sequence Map
    ChrX:141876886-141887293 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 64.02 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    204 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685231
 protein coding gene ChrX:141841655-141888326 (+)
129S1/SvImJ ENSMUSG00200045697
 protein coding gene ChrX:120896688-120901391 (+)
A/J ENSMUSG00195018898
 protein coding gene ChrX:124750065-124754778 (+)
AKR/J ENSMUSG00220035101
 protein coding gene ChrX:118188604-118193317 (+)
BALB/cJ ENSMUSG00180037011
 protein coding gene ChrX:121180140-121184851 (+)
C3H/HeJ ENSMUSG00175028903
 protein coding gene ChrX:125053856-125058559 (+)
C57BL/6NJ ENSMUSG00215043085
 protein coding gene ChrX:121652777-121657480 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033468
 protein coding gene ChrX:131544825-131549484 (+)
CAST/EiJ ENSTCUG00005036122
 protein coding gene ChrX:122264131-122268818 (+)
CBA/J ENSMUSG00210029646
 protein coding gene ChrX:121977776-121982479 (+)
DBA/2J ENSMUSG00185031554
 protein coding gene ChrX:135868636-135873339 (+)
FVB/NJ ENSMUSG00205027427
 protein coding gene ChrX:120359654-120364369 (+)
JF1/MsJ ENSUMUG00000018159
 protein coding gene ChrX:155123214-155127911 (+)
LP/J ENSMUSG00230032062
 protein coding gene ChrX:142497373-142502076 (+)
NOD/ShiLtJ ENSMUSG00190037379
 protein coding gene ChrX:121374456-121379173 (+)
NZO/HlLtJ ENSMUSG00225042042
 protein coding gene ChrX:147188332-147193035 (+)
PWK/PhJ ENSLUMG00010042979
 protein coding gene ChrX:119841893-119846624 (+)
SPRET/EiJ ENSMSPG00010034797
 protein coding gene ChrX:124574985-124579664 (+)
WSB/EiJ ENSIUOG00005037226
 protein coding gene ChrX:122010893-122015610 (+)



Homology
more
  • Human Ortholog
    RTL9, retrotransposon Gag like 9
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RTL9, retrotransposon Gag like 9
  • Synonyms
    MAR9, MART9, RGAG1, SIRH10
  • Links
    NCBI Gene ID: 57529
    UniProt: Q8NET4

  • Chr Location
    Xq23; chrX:110358848-110456334 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous mice lacking the C-terminal retroviral GAG-like region show impaired innate antifungal immunity showing loss of fungal zymosan degradation in microglial lysosomes.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    627
  • Tissues
    19
  • cDNA Data
    3
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000085584 Ensembl Gene Model | MGI Sequence Detail 10408 C57BL/6J ±  kb
transcript ENSMUST00000165829 Ensembl | MGI Sequence Detail 4333 Not Applicable  
polypeptide ENSMUSP00000128287 Ensembl | MGI Sequence Detail 1367 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 4
    cDNA 3
    Primer pair 1

    Microarray probesets 1
Other
Accession IDs
less
MGI:5906151
References
more
  • Summaries
    All 18
    Developmental Gene Expression 1
    Phenotypes 1
  • Earliest
    J:96508 Brandt J, et al., Transposable elements as a source of genetic innovation: expression and evolution of a family of retrotransposon-derived neogenes in mammals. Gene. 2005 Jan 17;345(1):101-11
  • Latest
    J:343808 Ishino F, et al., Retrovirus-Derived RTL9 Plays an Important Role in Innate Antifungal Immunity in the Eutherian Brain. Int J Mol Sci. 2023 Oct 4;24(19)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory