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Rtl3 Gene Detail
Summary
  • Symbol
    Rtl3
  • Name
    retrotransposon Gag like 3
  • Synonyms
    D430021I08Rik, Mar3, Mart3, Zcchc5, ZHC5
  • Feature Type
    protein coding gene
  • IDs
    MGI:2685221
    NCBI Gene: 213436
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:105880688-105884145 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 47.37 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    95 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2685221
 protein coding gene ChrX:105880688-105884250 (-)
129S1/SvImJ ENSMUSG00200037623
 protein coding gene ChrX:87663275-87666841 (-)
A/J ENSMUSG00195039841
 protein coding gene ChrX:91394505-91398067 (-)
AKR/J ENSMUSG00220036404
 protein coding gene ChrX:86117125-86120691 (-)
BALB/cJ ENSMUSG00180041795
 protein coding gene ChrX:88060624-88064187 (-)
C3H/HeJ ENSMUSG00175038832
 protein coding gene ChrX:91636427-91639989 (-)
C57BL/6NJ ENSMUSG00215044444
 protein coding gene ChrX:88289934-88293496 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033333
 protein coding gene ChrX:100847880-100851438 (-)
CAST/EiJ ENSTCUG00005038673
 protein coding gene ChrX:89093517-89097079 (-)
CBA/J ENSMUSG00210042024
 protein coding gene ChrX:88530034-88533596 (-)
DBA/2J ENSMUSG00185043667
 protein coding gene ChrX:101008522-101012088 (-)
FVB/NJ ENSMUSG00205031408
 protein coding gene ChrX:87605789-87609351 (-)
JF1/MsJ ENSUMUG00000015810
 protein coding gene ChrX:121598757-121602317 (-)
LP/J ENSMUSG00230042030
 protein coding gene ChrX:107660595-107664161 (-)
NOD/ShiLtJ ENSMUSG00190037716
 protein coding gene ChrX:87740685-87744251 (-)
NZO/HlLtJ ENSMUSG00225039649
 protein coding gene ChrX:112809413-112812975 (-)
PWK/PhJ ENSLUMG00010034796
 protein coding gene ChrX:86853937-86857497 (-)
SPRET/EiJ ENSMSPG00010036717
 protein coding gene ChrX:91141465-91144249 (-)
WSB/EiJ ENSIUOG00005041731
 protein coding gene ChrX:88249768-88253331 (-)



Homology
more
  • Human Ortholog
    RTL3, retrotransposon Gag like 3
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RTL3, retrotransposon Gag like 3
  • Synonyms
    Mar3, Mart3, SIRH9, ZCCHC5, ZHC5
  • Links
    NCBI Gene ID: 203430
    UniProt: Q8N8U3

  • Chr Location
    Xq21.1; chrX:78656068-78659532 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    736
  • Tissues
    38
  • cDNA Data
    10
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 213436 NCBI Gene Model | MGI Sequence Detail 3458 C57BL/6J ±  kb
transcript NM_199468 RefSeq | MGI Sequence Detail 2866 Not Specified  
polypeptide Q6P1Y1 UniProt | EBI | MGI Sequence Detail 553 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 10
    Primer pair 3
    Other 2

    Microarray probesets 1
Other
Accession IDs
less
MGI:5906149
References
more
  • Summaries
    All 27
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:96508 Brandt J, et al., Transposable elements as a source of genetic innovation: expression and evolution of a family of retrotransposon-derived neogenes in mammals. Gene. 2005 Jan 17;345(1):101-11
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory