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Slc25a51 Gene Detail
Summary
  • Symbol
    Slc25a51
  • Name
    solute carrier family 25, member 51
  • Synonyms
    9130208E07Rik, D130005A03Rik, Mcart1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2684984
    NCBI Gene: 230125
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:45395923-45408766 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 23.96 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    481 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2684984
 protein coding gene Chr4:45395923-45408922 (-)
129S1/SvImJ ENSMUSG00200002097
 protein coding gene Chr4:41450761-41463624 (-)
A/J ENSMUSG00195005856
 protein coding gene Chr4:41910763-41924195 (-)
AKR/J ENSMUSG00220002651
 protein coding gene Chr4:41595194-41608040 (-)
BALB/cJ ENSMUSG00180028123
 protein coding gene Chr4:41497446-41510884 (-)
C3H/HeJ ENSMUSG00175020110
 protein coding gene Chr4:41641677-41655113 (-)
C57BL/6NJ ENSMUSG00215012656
 protein coding gene Chr4:41418469-41431315 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025973
 protein coding gene Chr4:39450694-39464019 (-)
CAST/EiJ no annotation
CBA/J ENSMUSG00210018942
 protein coding gene Chr4:41331908-41344769 (-)
DBA/2J ENSMUSG00185032410
 protein coding gene Chr4:41695309-41708171 (-)
FVB/NJ ENSMUSG00205021882
 protein coding gene Chr4:40964201-40977048 (-)
JF1/MsJ ENSUMUG00000033323
 protein coding gene Chr4:41919924-41932811 (-)
LP/J ENSMUSG00230042273
 protein coding gene Chr4:45251846-45264707 (-)
NOD/ShiLtJ ENSMUSG00190025242
 protein coding gene Chr4:41553415-41566258 (-)
NZO/HlLtJ ENSMUSG00225005951
 protein coding gene Chr4:49846188-49859049 (-)
PWK/PhJ no annotation
SPRET/EiJ ENSMSPG00010008950
 protein coding gene Chr4:41849973-41859373 (-)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    SLC25A51, solute carrier family 25 member 51
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC25A51, solute carrier family 25 member 51
  • Synonyms
    CG7943, MCART1
  • Links
    NCBI Gene ID: 92014
    UniProt: Q9H1U9

  • Chr Location
    9p13.2-p13.1; chr9:37877575-37904387 (-)  GRCh38
  • Human Ortholog
    SLC25A52, solute carrier family 25 member 52
  • Synonyms
    MCART2
  • Links
    NCBI Gene ID: 147407
    UniProt: Q3SY17

  • Chr Location
    18q12.1; chr18:31759584-31760880 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    599
  • Tissues
    2
  • cDNA Data
    19
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000045973 Ensembl Gene Model | MGI Sequence Detail 12844 C57BL/6J ±  kb
transcript ENSMUST00000107796 Ensembl | MGI Sequence Detail 4433 Not Applicable  
polypeptide ENSMUSP00000103425 Ensembl | MGI Sequence Detail 315 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000029735 mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51
    (term hierarchy)
  • InterPro Domains
    IPR023395 Mitochondrial carrier protein domain superfamily
    IPR018108 Mitochondrial carrier protein, transmembrane region
    IPR052465 Mitochondrial NAD+ Carrier
  • GlyGen
    Q5HZI9 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 19
    cDNA 19

    Microarray probesets 5
Other
Accession IDs
less
MGI:1924920
References
more
  • Summaries
    All 48
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 15
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
  • Latest
    J:377381 Kong BS, et al., The mitochondrial NAD transporter SLC25A51 is a modulator of beta cell senescence and type 2 diabetes. bioRxiv. 2025;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory