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Gcnt4 Gene Detail
Summary
  • Symbol
    Gcnt4
  • Name
    glucosaminyl (N-acetyl) transferase 4, core 2 (beta-1,6-N-acetylglucosaminyltransferase)
  • Synonyms
    C2GNT3, Gm73, LOC218476, LOC238786
  • Feature Type
    protein coding gene
  • IDs
    MGI:2684919
    NCBI Gene: 218476
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:97061197-97087414 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 50.66 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    950 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2684919
 protein coding gene Chr13:97060852-97087422 (+)
129S1/SvImJ ENSMUSG00200008854
 protein coding gene Chr13:91587555-91613770 (+)
A/J ENSMUSG00195028697
 protein coding gene Chr13:92094820-92121075 (+)
AKR/J ENSMUSG00220013367
 protein coding gene Chr13:90544717-90570933 (+)
BALB/cJ ENSMUSG00180033325
 protein coding gene Chr13:92611928-92638145 (+)
C3H/HeJ ENSMUSG00175016564
 protein coding gene Chr13:92784093-92810309 (+)
C57BL/6NJ ENSMUSG00215020258
 protein coding gene Chr13:92663732-92689951 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018810
 protein coding gene Chr13:90554880-90580635 (+)
CAST/EiJ ENSTCUG00005010882
 protein coding gene Chr13:91866098-91892545 (+)
CBA/J ENSMUSG00210011131
 protein coding gene Chr13:92106193-92132423 (+)
DBA/2J ENSMUSG00185019194
 protein coding gene Chr13:95766874-95793102 (+)
FVB/NJ ENSMUSG00205017727
 protein coding gene Chr13:91577232-91603451 (+)
JF1/MsJ ENSUMUG00000026897
 protein coding gene Chr13:95463329-95489470 (+)
LP/J ENSMUSG00230036524
 protein coding gene Chr13:105772236-105798452 (+)
NOD/ShiLtJ ENSMUSG00190038300
 protein coding gene Chr13:92444445-92470663 (+)
NZO/HlLtJ ENSMUSG00225032751
 protein coding gene Chr13:98297945-98324161 (+)
PWK/PhJ ENSLUMG00010024019
 protein coding gene Chr13:91556493-91582685 (+)
SPRET/EiJ ENSMSPG00010008011
 protein coding gene Chr13:92822078-92845785 (+)
WSB/EiJ ENSIUOG00005032469
 protein coding gene Chr13:91473538-91499656 (+)



Homology
more
  • Human Ortholog
    GCNT4, glucosaminyl (N-acetyl) transferase 4
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GCNT4, glucosaminyl (N-acetyl) transferase 4
  • Synonyms
    C2GNT3, LINC01336
  • Links
    NCBI Gene ID: 51301
    UniProt: Q9P109

  • Chr Location
    5q13.3; chr5:75016969-75054224 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotypes from 2 alleles in 1 genetic background
    2 phenotypes from multigenic genotypes
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele display neutrophilia, increased aggression towards males, reduced serum thyroxine levels, and altered O-glycan structures in the stomach, colon, and small intestine.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    7
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000091387 Ensembl Gene Model | MGI Sequence Detail 26218 C57BL/6J ±  kb
    transcript ENSMUST00000171324 Ensembl | MGI Sequence Detail 5087 Not Applicable  
    polypeptide ENSMUSP00000130496 Ensembl | MGI Sequence Detail 455 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • Protein Ontology
      PR:000007906 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4
      (term hierarchy)
    • EC
      2.4.1.102
    • InterPro Domains
      IPR003406 Glycosyl transferase, family 14
    • GlyGen
      E9Q649 3 sites, 1 N-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 7
      cDNA 7

      Microarray probesets 1
    Other
    Accession IDs
    less
    MGI:2685125
    References
    more
    • Summaries
      All 29
      Gene Ontology 8
      Phenotypes 7
    • Earliest
      J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
    • Latest
      J:380781 Kopp Y, et al., CHIP as a membrane-shuttling proteostasis sensor. Elife. 2017 Nov 1;6:e29388
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory