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Scml1 Gene Detail
Summary
  • Symbol
    Scml1
  • Name
    Scm polycomb group protein like 1
  • Synonyms
    LOC195726, LOC386491
Location &
Maps
more
  • Sequence Map
    ChrX:160598170-160608319 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 74.15 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    241 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2684893
 protein coding gene ChrX:160597689-160615118 (-)
129S1/SvImJ ENSMUSG00200026935
 pseudogene ChrX:137320143-137337629 (-)
A/J ENSMUSG00195038103
 pseudogene ChrX:142444654-142462192 (-)
AKR/J ENSMUSG00220032387
 pseudogene ChrX:134301050-134318537 (-)
BALB/cJ ENSMUSG00180041500
 pseudogene ChrX:137818113-137835501 (-)
C3H/HeJ ENSMUSG00175027438
 pseudogene ChrX:142380688-142398174 (-)
C57BL/6NJ ENSMUSG00215027900
 pseudogene ChrX:138214997-138232485 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0006893
 lincRNA gene ChrX:150182278-150184293 (-)
CAST/EiJ ENSTCUG00005034104
 pseudogene ChrX:139961957-139979404 (-)
CBA/J ENSMUSG00210040104
 pseudogene ChrX:139718181-139735667 (-)
DBA/2J ENSMUSG00185031428
 pseudogene ChrX:154651603-154669040 (-)
FVB/NJ ENSMUSG00205032239
 pseudogene ChrX:138324968-138342455 (-)
JF1/MsJ ENSUMUG00000038185
 pseudogene ChrX:175025705-175043124 (-)
LP/J ENSMUSG00230014646
 pseudogene ChrX:161440992-161458428 (-)
NOD/ShiLtJ ENSMUSG00190036834
 pseudogene ChrX:138821363-138838849 (-)
NZO/HlLtJ ENSMUSG00225039036
 pseudogene ChrX:164830214-164847700 (-)
PWK/PhJ ENSLUMG00010042988
 pseudogene ChrX:136122544-136139935 (-)
SPRET/EiJ ENSMSPG00010020410
 pseudogene ChrX:141243614-141261178 (-)
WSB/EiJ ENSIUOG00005026204
 pseudogene ChrX:139110061-139127462 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous or hemizygous for a null mutation are viable and fertile but dense bodies are absent from almost all pachytene spermatocytes.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    2
Sequences &
Gene Models
less
  • All Sequences
    32
  • RefSeq
    10
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000086540 Ensembl Gene Model | MGI Sequence Detail 10150 C57BL/6J ±  kb
transcript ENSMUST00000238615 Ensembl | MGI Sequence Detail 551 Not Applicable  
polypeptide NP_001361133 RefSeq | MGI Sequence Detail 501 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 2
    cDNA 2
Other
Accession IDs
less
MGI:2686638
References
more
  • Summaries
    All 11
    Gene Ontology 1
    Phenotypes 1
  • Earliest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
  • Latest
    J:278848 Papanikos F, et al., The enigmatic meiotic dense body and its newly discovered component, SCML1, are dispensable for fertility and gametogenesis in mice. Chromosoma. 2017 Jun;126(3):399-415
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory