About   Help   FAQ
Uts2b Gene Detail
Summary
  • Symbol
    Uts2b
  • Name
    urotensin 2B
  • Synonyms
    Urp, Uts2d
  • Feature Type
    protein coding gene
  • IDs
    MGI:2677064
    NCBI Gene: 224065
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:27172072-27188989 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 16, 18.93 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    641 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2677064
protein coding gene Chr16:27172072-27188989 (-)
129S1/SvImJ ENSMUSG00200036132
protein coding gene Chr16:24200203-24217263 (-)
A/J ENSMUSG00195029068
protein coding gene Chr16:23737866-23754917 (-)
AKR/J ENSMUSG00220028169
protein coding gene Chr16:24069193-24086241 (-)
BALB/cJ ENSMUSG00180028791
protein coding gene Chr16:23967915-23984966 (-)
C3H/HeJ ENSMUSG00175037483
protein coding gene Chr16:24120537-24137592 (-)
C57BL/6NJ ENSMUSG00215019341
protein coding gene Chr16:23853858-23870930 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020633
protein coding gene Chr16:24483745-24499019 (-)
CAST/EiJ ENSTCUG00005035380
protein coding gene Chr16:24433280-24450234 (-)
CBA/J ENSMUSG00210036926
protein coding gene Chr16:24142759-24159815 (-)
DBA/2J ENSMUSG00185019275
protein coding gene Chr16:24081631-24098687 (-)
FVB/NJ ENSMUSG00205021386
protein coding gene Chr16:24073800-24090853 (-)
JF1/MsJ ENSUMUG00000033689
protein coding gene Chr16:24279498-24296344 (-)
LP/J ENSMUSG00230032423
protein coding gene Chr16:26651647-26668703 (-)
NOD/ShiLtJ ENSMUSG00190029550
protein coding gene Chr16:24255281-24272334 (-)
NZO/HlLtJ ENSMUSG00225036846
protein coding gene Chr16:29896762-29913788 (-)
PWK/PhJ ENSLUMG00010031645
protein coding gene Chr16:24088161-24104929 (-)
SPRET/EiJ ENSMSPG00010016265
protein coding gene Chr16:24019626-24036400 (-)
WSB/EiJ ENSIUOG00005033328
protein coding gene Chr16:24337898-24354927 (-)



Homology
more
  • Human Ortholog
    UTS2B, urotensin 2B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    UTS2B, urotensin 2B
  • Synonyms
    U2B, U-IIB, UIIB, URP, UTS2D
  • Links
    NCBI Gene ID: 257313
    UniProt: Q765I0

  • Chr Location
    3q28; chr3:191267168-191346182 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 224065 NCBI Gene Model | MGI Sequence Detail 16918 C57BL/6J ±  kb
    transcript NM_198166 RefSeq | MGI Sequence Detail 851 C57BL/6  
    polypeptide Q765I1 UniProt | EBI | MGI Sequence Detail 113 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 8
      cDNA 7
      Primer pair 1

      Microarray probesets 1
    Other
    Accession IDs
    less
    MGI:2685384
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 6
      Gene Ontology 4
      Phenotypes 9
    • Earliest
      J:87485 Sugo T, et al., Identification of urotensin II-related peptide as the urotensin II-immunoreactive molecule in the rat brain. Biochem Biophys Res Commun. 2003 Oct 24;310(3):860-8
    • Latest
      J:377967 Roome RB, et al., Ontogeny of the spinal cord dorsal horn. Science. 2026 Jan 8;391(6781):eadx5781

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.
    last database update
    09/08/2026
    MGI 6.24
    The Jackson Laboratory