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Scgb1c1 Gene Detail
Summary
  • Symbol
    Scgb1c1
  • Name
    secretoglobin, family 1C, member 1
  • Synonyms
    Ryd5
  • Feature Type
    protein coding gene
  • IDs
    MGI:2655401
    NCBI Gene: 338417
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:140425478-140426682 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 86.04 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    140 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2655401
 protein coding gene Chr7:140425460-140426682 (+)
129S1/SvImJ ENSMUSG00200045013
 protein coding gene Chr7:126990203-126991425 (+)
A/J ENSMUSG00195038830
 protein coding gene Chr7:131472630-131473852 (+)
AKR/J ENSMUSG00220029169
 protein coding gene Chr7:124944233-124945455 (+)
BALB/cJ ENSMUSG00180029496
 protein coding gene Chr7:128164795-128166017 (+)
C3H/HeJ ENSMUSG00175034931
 protein coding gene Chr7:128893104-128894326 (+)
C57BL/6NJ ENSMUSG00215045453
 protein coding gene Chr7:128159649-128160871 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030660
 protein coding gene Chr7:143038772-143040001 (+)
CAST/EiJ ENSTCUG00005047935
 protein coding gene Chr7:131465842-131467064 (+)
CBA/J ENSMUSG00210029638
 protein coding gene Chr7:128651097-128652319 (+)
DBA/2J ENSMUSG00185016917
 protein coding gene Chr7:132929664-132930886 (+)
FVB/NJ ENSMUSG00205043531
 protein coding gene Chr7:128571930-128573152 (+)
JF1/MsJ ENSUMUG00000015625
 protein coding gene Chr7:138006944-138008166 (+)
LP/J ENSMUSG00230038745
 protein coding gene Chr7:139093168-139094390 (+)
NOD/ShiLtJ ENSMUSG00190019474
 protein coding gene Chr7:128758573-128759795 (+)
NZO/HlLtJ ENSMUSG00225048693
 protein coding gene Chr7:137302404-137303626 (+)
PWK/PhJ ENSLUMG00010043641
 protein coding gene Chr7:127137880-127139102 (+)
SPRET/EiJ ENSMSPG00010036362
 protein coding gene Chr7:128578356-128579578 (+)
WSB/EiJ ENSIUOG00005029603
 protein coding gene Chr7:129493592-129494814 (+)



Homology
more
  • Human Ortholog
    SCGB1C1, secretoglobin family 1C member 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SCGB1C1, secretoglobin family 1C member 1
  • Synonyms
    RYD5
  • Links
    NCBI Gene ID: 147199
    UniProt: Q8TD33

  • Chr Location
    11p15.5; chr11:188050-194575 (+)  GRCh38
  • Human Ortholog
    SCGB1C2, secretoglobin family 1C member 2
  • Links
    NCBI Gene ID: 653486
    UniProt: P0DMR2

  • Chr Location
    17p13.3; chr17:137569-139067 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    8
  • Endonuclease-mediated
    1
  • Gene trapped
    4
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    1 involving Scgb1c1
  • Find Mice (IMSR)
    9 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 338417 NCBI Gene Model | MGI Sequence Detail 1205 C57BL/6J ±  kb
transcript NM_001099742 RefSeq | MGI Sequence Detail 451 C57BL/6  
polypeptide Q7M742 UniProt | EBI | MGI Sequence Detail 95 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 2
References
more
  • Summaries
    All 30
    Gene Ontology 1
    Phenotypes 12
  • Earliest
    J:65007 Cattanach BM, et al., Two imprinted gene mutations: three phenotypes. Hum Mol Genet. 2000 Sep 22;9(15):2263-73
  • Latest
    J:367412 Kim SD, et al., SCGB1C1 Plays a Critical Role in Suppression of Allergic Airway Inflammation through the Induction of Regulatory T Cell Expansion. Int J Mol Sci. 2024 Jun 6;25(11)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory