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Tmem185a Gene Detail
Summary
  • Symbol
    Tmem185a
  • Name
    transmembrane protein 185A
  • Synonyms
    BC023829, ee3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2448555
    NCBI Gene: 236848
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:69503359-69520786 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 36.04 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    372 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2448555
 protein coding gene ChrX:69503359-69520796 (-)
129S1/SvImJ ENSMUSG00200040156
 protein coding gene ChrX:51630838-51648276 (-)
A/J ENSMUSG00195031994
 protein coding gene ChrX:55244160-55261596 (-)
AKR/J ENSMUSG00220045194
 protein coding gene ChrX:50550107-50567543 (+)
BALB/cJ ENSMUSG00180047579
 protein coding gene ChrX:51843819-51861255 (-)
C3H/HeJ ENSMUSG00175029655
 protein coding gene ChrX:55412767-55430205 (-)
C57BL/6NJ ENSMUSG00215040357
 protein coding gene ChrX:51896949-51914379 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033127
 protein coding gene ChrX:65117483-65135399 (-)
CAST/EiJ ENSTCUG00005038750
 protein coding gene ChrX:53398276-53415695 (+)
CBA/J ENSMUSG00210043828
 protein coding gene ChrX:52084369-52101805 (-)
DBA/2J ENSMUSG00185030087
 protein coding gene ChrX:64533253-64550689 (-)
FVB/NJ no annotation
JF1/MsJ ENSUMUG00000043541
 protein coding gene ChrX:85368304-85386368 (+)
LP/J ENSMUSG00230032771
 protein coding gene ChrX:71089124-71106560 (-)
NOD/ShiLtJ ENSMUSG00190028892
 protein coding gene ChrX:51344349-51361785 (-)
NZO/HlLtJ ENSMUSG00225048348
 protein coding gene ChrX:76296504-76313940 (+)
PWK/PhJ ENSLUMG00010044245
 protein coding gene ChrX:51231945-51249977 (-)
SPRET/EiJ ENSMSPG00010036192
 protein coding gene ChrX:54232492-54250430 (-)
WSB/EiJ ENSIUOG00005046686
 protein coding gene ChrX:52312172-52329657 (-)



Homology
more
  • Human Ortholog
    TMEM185A, transmembrane protein 185A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM185A, transmembrane protein 185A
  • Synonyms
    CXorf13, ee3, FAM11A, FRAXF
  • Links
    NCBI Gene ID: 84548
    UniProt: Q8NFB2

  • Chr Location
    Xq28; chrX:149596556-149631912 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    47
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000073139 Ensembl Gene Model | MGI Sequence Detail 17428 C57BL/6J ±  kb
transcript ENSMUST00000114630 Ensembl | MGI Sequence Detail 1307 Not Applicable  
polypeptide ENSMUSP00000110277 Ensembl | MGI Sequence Detail 350 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 47
    cDNA 47

    Microarray probesets 3
References
more
  • Summaries
    All 32
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:131693 Maurer MH, et al., Cloning of a novel neuronally expressed orphan G-protein-coupled receptor which is up-regulated by erythropoietin, interacts with microtubule-associated protein 1b and colocalizes with the 5-hydroxytryptamine 2a receptor. J Neurochem. 2004 Nov;91(4):1007-17
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory