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H3c6 Gene Detail
Summary
  • Symbol
    H3c6
  • Name
    H3 clustered histone 6
  • Synonyms
    H3.1, H3-f, Hist1h3e
  • Feature Type
    protein coding gene
  • IDs
    MGI:2448326
    NCBI Gene: 319151
  • Member of
    Hist1 cluster
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:23745708-23746543 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 9.79 cM, cytoband A2-A3
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    141 from dbSNP Build 142
  • Strain Annotations
    5
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2448326
 protein coding gene Chr13:23745649-23746559 (-)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ ENSMUSG00215011076
 protein coding gene Chr13:20502762-20503597 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018320
 protein coding gene Chr13:19402984-19403773 (-)
CAST/EiJ ENSTCUG00005010074
 protein coding gene Chr13:20528915-20529724 (-)
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
JF1/MsJ no annotation
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ ENSIUOG00005031960
 protein coding gene Chr13:19642690-19643499 (-)



Homology
more
  • Human Ortholog
    H3C13, H3 clustered histone 13
  • Vertebrate Orthologs
    10
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    H3C13, H3 clustered histone 13
  • Synonyms
    HIST2H3D
  • Links
    NCBI Gene ID: 653604
    UniProt: Q71DI3

  • Chr Location
    1q21.2; chr1:149813225-149813693 (-)  GRCh38
  • Human Ortholog
    H3C14, H3 clustered histone 14
  • Synonyms
    H3, H3.2, H3F2, H3FM, H3FN, H3/M, HIST2H3C
  • Links
    NCBI Gene ID: 126961
    UniProt: Q71DI3

  • Chr Location
    1q21.2; chr1:149840687-149841208 (-)  GRCh38
  • Human Ortholog
    H3C15, H3 clustered histone 15
  • Synonyms
    H3/n, H3/o, HIST2H3A
  • Links
    NCBI Gene ID: 333932
    UniProt: Q71DI3

  • Chr Location
    1q21.2; chr1:149852608-149853125 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Gene trapped
    1
  • Radiation induced
    1
  • Genomic Mutations
    2 involving H3c6
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    8 strains or lines available
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    613
  • Tissues
    15
  • cDNA Data
    3
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000069273 Ensembl Gene Model | MGI Sequence Detail 836 C57BL/6J ±  kb
transcript ENSMUST00000105107 Ensembl | MGI Sequence Detail 836 Not Applicable  
polypeptide ENSMUSP00000100739 Ensembl | MGI Sequence Detail 136 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 5
    Genomic 1
    cDNA 3
    Primer pair 1
Other
Accession IDs
less
MGI:6324983
References
more
  • Summaries
    All 39
    Developmental Gene Expression 1
    Phenotypes 12
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:391040 Funaya S, et al., H3.1/3.2 regulate the initial progression of the gene expression program. Nucleic Acids Res. 2024 Jun 24;52(11):6158-6170
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory