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Pwwp3b Gene Detail
Summary
  • Symbol
    Pwwp3b
  • Name
    PWWP domain containing 3B
  • Synonyms
    9430086K21Rik, Mum1l1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2445062
    NCBI Gene: 245631
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:138110791-138139084 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 61.29 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    572 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2445062
 protein coding gene ChrX:138110726-138139084 (+)
129S1/SvImJ ENSMUSG00200045043
 protein coding gene ChrX:117114488-117142785 (+)
A/J ENSMUSG00195046843
 protein coding gene ChrX:120973461-121001762 (+)
AKR/J ENSMUSG00220036397
 protein coding gene ChrX:114421534-114449830 (+)
BALB/cJ ENSMUSG00180033468
 protein coding gene ChrX:117406192-117434491 (+)
C3H/HeJ ENSMUSG00175029273
 protein coding gene ChrX:121273931-121302218 (+)
C57BL/6NJ ENSMUSG00215043111
 protein coding gene ChrX:117818861-117847161 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033439
 protein coding gene ChrX:127865872-127893945 (+)
CAST/EiJ ENSTCUG00005038751
 protein coding gene ChrX:118473730-118502023 (+)
CBA/J ENSMUSG00210034931
 protein coding gene ChrX:118200864-118229154 (+)
DBA/2J ENSMUSG00185028415
 protein coding gene ChrX:132092464-132120752 (+)
FVB/NJ ENSMUSG00205025664
 protein coding gene ChrX:116602590-116630886 (+)
JF1/MsJ ENSUMUG00000017833
 protein coding gene ChrX:151340809-151369027 (+)
LP/J ENSMUSG00230038786
 protein coding gene ChrX:138715525-138743819 (+)
NOD/ShiLtJ ENSMUSG00190033745
 protein coding gene ChrX:117607326-117635619 (+)
NZO/HlLtJ ENSMUSG00225041778
 protein coding gene ChrX:143411239-143439539 (+)
PWK/PhJ ENSLUMG00010043066
 protein coding gene ChrX:116096439-116124632 (+)
SPRET/EiJ ENSMSPG00010035436
 protein coding gene ChrX:120725041-120731768 (+)
WSB/EiJ ENSIUOG00005036238
 protein coding gene ChrX:118286956-118315257 (+)



Homology
more
  • Human Ortholog
    PWWP3B, PWWP domain containing 3B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PWWP3B, PWWP domain containing 3B
  • Synonyms
    MUM1L1
  • Links
    NCBI Gene ID: 139221
    UniProt: Q5H9M0

  • Chr Location
    Xq22.3; chrX:106168304-106208963 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    647
  • Tissues
    5
  • cDNA Data
    28
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000042515 Ensembl Gene Model | MGI Sequence Detail 28294 C57BL/6J ±  kb
transcript ENSMUST00000113045 Ensembl | MGI Sequence Detail 4523 Not Applicable  
polypeptide ENSMUSP00000108668 Ensembl | MGI Sequence Detail 681 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000010776 PWWP domain-containing DNA repair factor 3B
    (term hierarchy)
  • InterPro Domains
    IPR035504 MUM1-like, PWWP domain
    IPR040263 PWWP domain-containing DNA repair factor 3A/3B/4
    IPR048795 PWWP domain-containing DNA repair factor 3A/3B/4, C-terminal
    IPR048765 PWWP domain-containing DNA repair factor 3A/3B/4, N-terminal
Molecular
Reagents
less
  • All nucleic 31
    Genomic 2
    cDNA 28
    Primer pair 1

    Microarray probesets 2
Other
Accession IDs
less
MGI:6277123
References
more
  • Summaries
    All 29
    Developmental Gene Expression 2
    Phenotypes 9
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:380581 Cakir Z, et al., Quantitative Proteomic Analysis Reveals apoE4-Dependent Phosphorylation of the Actin-Regulating Protein VASP. Mol Cell Proteomics. 2023 May;22(5):100541
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory