Ifitm10 MGI Mouse Gene Detail - MGI:2444776 - interferon induced transmembrane protein 10

Symbol

Ifitm10
Name

interferon induced transmembrane protein 10
Synonyms

6330512M04Rik

Feature Type

protein coding gene
IDs

MGI:2444776
NCBI Gene: 320802
Alliance

genome feature page
Transcription Start Sites

7 TSS

Sequence Map

Chr7:141879574-141927490 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 7, 87.90 cM
Mapping Data

2 experiments

SNPs within 2kb

1315 from dbSNP Build 142
Strain Annotations

14

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2444776	protein coding gene	Chr7:141879572-141927526 (-)
129S1/SvImJ	ENSMUSG00200042999	protein coding gene	Chr7:128446190-128493844 (-)
A/J	ENSMUSG00195033848	protein coding gene	Chr7:132928232-132975883 (-)
AKR/J	ENSMUSG00220031111	protein coding gene	Chr7:126410455-126458111 (-)
BALB/cJ	ENSMUSG00180037678	protein coding gene	Chr7:129615282-129663521 (-)
C3H/HeJ	ENSMUSG00175030426	protein coding gene	Chr7:130349150-130396792 (-)
C57BL/6NJ	ENSMUSG00215044490	protein coding gene	Chr7:129615516-129663162 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0030720	protein coding gene	Chr7:144523598-144573611 (-)
CAST/EiJ	no annotation
CBA/J	ENSMUSG00210026356	protein coding gene	Chr7:130107077-130154726 (-)
DBA/2J	ENSMUSG00185015199	protein coding gene	Chr7:134385667-134433323 (-)
FVB/NJ	ENSMUSG00205030965	protein coding gene	Chr7:130027809-130075452 (-)
JF1/MsJ	no annotation
LP/J	ENSMUSG00230041591	protein coding gene	Chr7:140549024-140596669 (-)
NOD/ShiLtJ	ENSMUSG00190027071	protein coding gene	Chr7:130214572-130262223 (-)
NZO/HlLtJ	ENSMUSG00225050312	protein coding gene	Chr7:138757947-138805593 (-)
PWK/PhJ	no annotation
SPRET/EiJ	no annotation
WSB/EiJ	no annotation

Human Ortholog

IFITM10, interferon induced transmembrane protein 10

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

IFITM10, interferon induced transmembrane protein 10
Synonyms

DSPA3
Links

HGNC:40022

NCBI Gene ID: 402778

UniProt: A6NMD0
Chr Location

11p15.5; chr11:1732406-1750605 (-) GRCh38

MGI Vertebrate Homology

Ifitm10 stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: IFITM10
Gene Tree

Ifitm10

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Phenotype Summary

7 phenotype references

All Mutations and Alleles

4
Endonuclease-mediated

2
Radiation induced

1
Targeted

1
Genomic Mutations

1 involving Ifitm10
Incidental Mutations

APF
Find Mice (IMSR)

15 strains or lines available

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All GO Annotations

3
GO References

3

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

597
cDNA Data

19

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase ifitm10

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All Sequences

64
RefSeq

30
UniProt

1
CCDS

CCDS40191.1, CCDS85467.1, CCDS85468.1

Ensembl

ENSMUSG00000045777 (Evidence)
NCBI Gene

320802

			Length	Strain/Species	Flank
genomic	ENSMUSG00000045777	Ensembl Gene Model \| MGI Sequence Detail	47917	C57BL/6J	± kb
transcript	ENSMUST00000105988	Ensembl \| MGI Sequence Detail	824	Not Applicable
polypeptide	ENSMUSP00000101608	Ensembl \| MGI Sequence Detail	201	Not Applicable

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UniProt

1 Sequence
Protein Ontology

PR:000032144 interferon-induced transmembrane protein 10

(term hierarchy)
InterPro Domains

IPR007593 CD225/Dispanin family

IPR051517 Interferon-induced transmembrane antiviral protein

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All nucleic 19

cDNA 19

Microarray probesets 3

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MGI:2142050

Summaries

All 31

Gene Ontology 3

Phenotypes 7
Earliest

J:65007 Cattanach BM, et al., Two imprinted gene mutations: three phenotypes. Hum Mol Genet. 2000 Sep 22;9(15):2263-73
Latest

J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

TSS for Ifitm10:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr75749	Chr7:141927470-141927508 (-)	1 bp
Tssr75748	Chr7:141926478-141926512 (-)	995 bp
Tssr75747	Chr7:141926079-141926108 (-)	1,396 bp
Tssr75746	Chr7:141926058-141926073 (-)	1,424 bp
Tssr75745	Chr7:141925947-141926029 (-)	1,502 bp
Tssr75744	Chr7:141924838-141924847 (-)	2,647 bp
Tssr75743	Chr7:141895762-141895767 (-)	31,725 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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