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Fastkd1 Gene Detail
Summary
  • Symbol
    Fastkd1
  • Name
    FAST kinase domains 1
  • Synonyms
    5330408N05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444596
    NCBI Gene: 320720
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:69517159-69543860 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 40.93 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    842 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444596
 protein coding gene Chr2:69517159-69543875 (-)
129S1/SvImJ ENSMUSG00200036847
 protein coding gene Chr2:66576524-66602314 (-)
A/J ENSMUSG00195021003
 protein coding gene Chr2:66727519-66753334 (-)
AKR/J ENSMUSG00220034945
 protein coding gene Chr2:66692399-66718217 (-)
BALB/cJ ENSMUSG00180036349
 protein coding gene Chr2:66672762-66698551 (-)
C3H/HeJ ENSMUSG00175035391
 protein coding gene Chr2:66792107-66817890 (-)
C57BL/6NJ ENSMUSG00215018938
 protein coding gene Chr2:66612933-66638728 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023624
 protein coding gene Chr2:64213370-64239497 (-)
CAST/EiJ ENSTCUG00005008894
 protein coding gene Chr2:66092744-66118525 (-)
CBA/J ENSMUSG00210036841
 protein coding gene Chr2:66832378-66858164 (-)
DBA/2J ENSMUSG00185038225
 protein coding gene Chr2:66667915-66693696 (-)
FVB/NJ ENSMUSG00205028266
 protein coding gene Chr2:66142445-66168257 (-)
JF1/MsJ ENSUMUG00000003527
 protein coding gene Chr2:66332181-66357958 (-)
LP/J ENSMUSG00230018401
 protein coding gene Chr2:68473396-68499183 (-)
NOD/ShiLtJ ENSMUSG00190030365
 protein coding gene Chr2:66760953-66786764 (-)
NZO/HlLtJ ENSMUSG00225014276
 protein coding gene Chr2:76215661-76241443 (-)
PWK/PhJ ENSLUMG00010030196
 protein coding gene Chr2:66558147-66583957 (-)
SPRET/EiJ ENSMSPG00010034314
 protein coding gene Chr2:67957007-67983163 (-)
WSB/EiJ ENSIUOG00005017724
 protein coding gene Chr2:66806557-66832373 (-)



Homology
more
  • Human Ortholog
    FASTKD1, FASTK mitochondrial RNA regulator 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FASTKD1, FASTK mitochondrial RNA regulator 1
  • Links
    NCBI Gene ID: 79675
    UniProt: Q53R41

  • Chr Location
    2q31.1; chr2:169528508-169573912 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    602
  • Tissues
    3
  • cDNA Data
    24
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000027086 Ensembl Gene Model | MGI Sequence Detail 26702 C57BL/6J ±  kb
transcript ENSMUST00000073152 Ensembl | MGI Sequence Detail 2865 Not Applicable  
polypeptide ENSMUSP00000072896 Ensembl | MGI Sequence Detail 829 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 25
    cDNA 25

    Microarray probesets 3
References
more
  • Summaries
    All 35
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 9
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:279266 Marshall KD, et al., The novel cyclophilin-D-interacting protein FASTKD1 protects cells against oxidative stress-induced cell death. Am J Physiol Cell Physiol. 2019 Sep 1;317(3):C584-C599
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory