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Flad1 Gene Detail
Summary
  • Symbol
    Flad1
  • Name
    flavin adenine dinucleotide synthetase 1
  • Synonyms
    A930017E24Rik, Pp591
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443030
    NCBI Gene: 319945
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:89309980-89319188 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 3, 39.10 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    277 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443030
protein coding gene Chr3:89308311-89319188 (-)
129S1/SvImJ ENSMUSG00200037738
protein coding gene Chr3:86163558-86174424 (-)
A/J ENSMUSG00195050721
protein coding gene Chr3:86178584-86189452 (-)
AKR/J ENSMUSG00220048512
protein coding gene Chr3:86133142-86144009 (-)
BALB/cJ ENSMUSG00180046784
protein coding gene Chr3:86260671-86271539 (-)
C3H/HeJ ENSMUSG00175043284
protein coding gene Chr3:86111203-86122070 (-)
C57BL/6NJ ENSMUSG00215048158
protein coding gene Chr3:86551320-86562187 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025208
protein coding gene Chr3:82131285-82142135 (-)
CAST/EiJ ENSTCUG00005044156
protein coding gene Chr3:85626916-85637756 (-)
CBA/J ENSMUSG00210037970
protein coding gene Chr3:86248841-86259707 (-)
DBA/2J ENSMUSG00185046999
protein coding gene Chr3:86349121-86359987 (-)
FVB/NJ ENSMUSG00205047614
protein coding gene Chr3:85172811-85183678 (-)
JF1/MsJ ENSUMUG00000030494
protein coding gene Chr3:85957754-85968548 (-)
LP/J ENSMUSG00230031892
protein coding gene Chr3:88384862-88395728 (-)
NOD/ShiLtJ ENSMUSG00190034170
protein coding gene Chr3:86634014-86644883 (-)
NZO/HlLtJ ENSMUSG00225007572
protein coding gene Chr3:91140149-91151015 (-)
PWK/PhJ ENSLUMG00010044652
protein coding gene Chr3:85999579-86010379 (-)
SPRET/EiJ ENSMSPG00010049007
protein coding gene Chr3:86862207-86873058 (-)
WSB/EiJ ENSIUOG00005049501
protein coding gene Chr3:86655366-86666232 (-)



Homology
more
  • Human Ortholog
    FLAD1, flavin adenine dinucleotide synthetase 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FLAD1, flavin adenine dinucleotide synthetase 1
  • Synonyms
    FAD1, FADS, LSMFLAD, PP591
  • Links
    NCBI Gene ID: 80308
    UniProt: Q8NFF5

  • Chr Location
    1q21.3; chr1:154983338-154993111 (+)  GRCh38

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 319945 NCBI Gene Model | MGI Sequence Detail 9209 C57BL/6J ±  kb
transcript NM_001362376 RefSeq | MGI Sequence Detail 2429 C57BL/6  
polypeptide Q8R123 UniProt | EBI | MGI Sequence Detail 492 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 2
References
more
  • Summaries
    All 44
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 13
    Phenotypes 10
  • Earliest
    J:335799 DELUCA C, et al., Flavin adenine dinucleotide synthesis in animal tissues. Biochim Biophys Acta. 1958 Oct;30(1):6-11
  • Latest
    J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/08/2026
MGI 6.24
The Jackson Laboratory