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Aasdh Gene Detail
Summary
  • Symbol
    Aasdh
  • Name
    aminoadipate-semialdehyde dehydrogenase
  • Synonyms
    A230062G08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442517
    NCBI Gene: 231326
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:77021506-77053361 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 41.45 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1051 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442517
 protein coding gene Chr5:77021506-77053376 (-)
129S1/SvImJ ENSMUSG00200000622
 protein coding gene Chr5:72714082-72740413 (-)
A/J ENSMUSG00195010161
 protein coding gene Chr5:72029774-72056045 (-)
AKR/J ENSMUSG00220014768
 protein coding gene Chr5:72141523-72167827 (-)
BALB/cJ ENSMUSG00180000039
 protein coding gene Chr5:71785875-71812208 (-)
C3H/HeJ ENSMUSG00175004122
 protein coding gene Chr5:73830815-73857123 (-)
C57BL/6NJ ENSMUSG00215000429
 protein coding gene Chr5:72600451-72626776 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027320
 protein coding gene Chr5:69775448-69809240 (-)
CAST/EiJ ENSTCUG00005013114
 protein coding gene Chr5:71580771-71608529 (-)
CBA/J ENSMUSG00210000421
 protein coding gene Chr5:72768756-72795067 (-)
DBA/2J ENSMUSG00185015663
 protein coding gene Chr5:74598712-74625014 (-)
FVB/NJ ENSMUSG00205020114
 protein coding gene Chr5:71557010-71583323 (-)
JF1/MsJ ENSUMUG00000005612
 protein coding gene Chr5:79087851-79117847 (-)
LP/J ENSMUSG00230019573
 protein coding gene Chr5:79288044-79314372 (-)
NOD/ShiLtJ ENSMUSG00190007633
 protein coding gene Chr5:71720038-71746368 (-)
NZO/HlLtJ ENSMUSG00225033810
 protein coding gene Chr5:84335036-84361365 (-)
PWK/PhJ ENSLUMG00010007453
 protein coding gene Chr5:71663226-71691223 (-)
SPRET/EiJ ENSMSPG00010009589
 protein coding gene Chr5:73662409-73693201 (-)
WSB/EiJ ENSIUOG00005017812
 protein coding gene Chr5:74565882-74592228 (-)



Homology
more
  • Human Ortholog
    AASDH, aminoadipate-semialdehyde dehydrogenase
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    AASDH, aminoadipate-semialdehyde dehydrogenase
  • Synonyms
    ACSF4, LYS2, NRPS1098, NRPS998
  • Links
    NCBI Gene ID: 132949
    UniProt: Q4L235

  • Chr Location
    4q12; chr4:56337994-56387523 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    23
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000055923 Ensembl Gene Model | MGI Sequence Detail 31856 C57BL/6J ±  kb
    transcript ENSMUST00000120963 Ensembl | MGI Sequence Detail 3694 Not Applicable  
    polypeptide ENSMUSP00000113792 Ensembl | MGI Sequence Detail 1100 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 23
      cDNA 23

      Microarray probesets 2
    References
    more
    • Summaries
      All 36
      Gene Ontology 3
      Phenotypes 14
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/15/2026
    MGI 6.29     		The Jackson Laboratory