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Dpep2 Gene Detail
Summary
  • Symbol
    Dpep2
  • Name
    dipeptidase 2
  • Synonyms
    F630103D06Rik, MBD-2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442042
    NCBI Gene: 319446
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:106711577-106732658 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 53.07 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    600 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442042
 protein coding gene Chr8:106711576-106732658 (-)
129S1/SvImJ ENSMUSG00200012291
 protein coding gene Chr8:100991450-100998267 (-)
A/J ENSMUSG00195019442
 protein coding gene Chr8:101313950-101320766 (-)
AKR/J ENSMUSG00220015034
 protein coding gene Chr8:101456573-101463388 (-)
BALB/cJ ENSMUSG00180023761
 protein coding gene Chr8:101319739-101326555 (-)
C3H/HeJ ENSMUSG00175023070
 protein coding gene Chr8:101376439-101383254 (-)
C57BL/6NJ ENSMUSG00215022633
 protein coding gene Chr8:100990788-100997606 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031508
 protein coding gene Chr8:97116505-97128631 (-)
CAST/EiJ ENSTCUG00005021111
 protein coding gene Chr8:100758135-100764943 (-)
CBA/J ENSMUSG00210034067
 protein coding gene Chr8:101304164-101310981 (-)
DBA/2J ENSMUSG00185005439
 protein coding gene Chr8:107412920-107419735 (-)
FVB/NJ ENSMUSG00205011648
 protein coding gene Chr8:100288488-100295304 (-)
JF1/MsJ ENSUMUG00000008141
 protein coding gene Chr8:109746105-109752920 (-)
LP/J ENSMUSG00230032616
 protein coding gene Chr8:111093313-111100127 (-)
NOD/ShiLtJ ENSMUSG00190019702
 protein coding gene Chr8:101443338-101450153 (-)
NZO/HlLtJ ENSMUSG00225022171
 protein coding gene Chr8:114443866-114450681 (-)
PWK/PhJ ENSLUMG00010003852
 protein coding gene Chr8:101240280-101247110 (-)
SPRET/EiJ ENSMSPG00010036671
 protein coding gene Chr8:103305852-103312717 (-)
WSB/EiJ ENSIUOG00005032302
 protein coding gene Chr8:102123767-102130578 (-)



Homology
more
  • Human Ortholog
    DPEP2, dipeptidase 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DPEP2, dipeptidase 2
  • Synonyms
    MBD2
  • Links
    NCBI Gene ID: 64174
    UniProt: Q9H4A9

  • Chr Location
    16q22.1; chr16:67987390-68000619 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
    14
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 319446 NCBI Gene Model | MGI Sequence Detail 21082 C57BL/6J ±  kb
transcript NM_176913 RefSeq | MGI Sequence Detail 1878 C57BL/6  
polypeptide Q8C255 UniProt | EBI | MGI Sequence Detail 478 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 2
References
more
  • Summaries
    All 34
    Gene Ontology 9
    Phenotypes 9
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:290679 Yang X, et al., Dpep2 Emerging as a Modulator of Macrophage Inflammation Confers Protection Against CVB3-Induced Viral Myocarditis. Front Cell Infect Microbiol. 2019;9:57
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory