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Plppr3 Gene Detail
Summary
  • Symbol
    Plppr3
  • Name
    phospholipid phosphatase related 3
  • Synonyms
    BC005764, Lppr3, PRG-2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2388640
    NCBI Gene: 216152
  • Alliance
    genome feature page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:79696309-79710468 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 39.72 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    262 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2388640
 protein coding gene Chr10:79696309-79710948 (-)
129S1/SvImJ ENSMUSG00200048815
 protein coding gene Chr10:76319981-76334143 (-)
A/J ENSMUSG00195038535
 protein coding gene Chr10:76715467-76729632 (-)
AKR/J ENSMUSG00220042092
 protein coding gene Chr10:76313030-76327192 (-)
BALB/cJ ENSMUSG00180045733
 protein coding gene Chr10:76725953-76740114 (-)
C3H/HeJ ENSMUSG00175051723
 protein coding gene Chr10:76596685-76610847 (-)
C57BL/6NJ ENSMUSG00215050978
 protein coding gene Chr10:76338377-76352543 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015546
 protein coding gene Chr10:73840653-73856080 (-)
CAST/EiJ ENSTCUG00005050186
 protein coding gene Chr10:76223273-76237193 (-)
CBA/J ENSMUSG00210047212
 protein coding gene Chr10:76452775-76466935 (-)
DBA/2J ENSMUSG00185047321
 protein coding gene Chr10:76795152-76809314 (-)
FVB/NJ ENSMUSG00205046153
 protein coding gene Chr10:76507941-76522101 (-)
JF1/MsJ ENSUMUG00000043890
 protein coding gene Chr10:78025514-78039639 (-)
LP/J ENSMUSG00230045184
 protein coding gene Chr10:78564899-78579059 (-)
NOD/ShiLtJ ENSMUSG00190047850
 protein coding gene Chr10:76708903-76723066 (-)
NZO/HlLtJ ENSMUSG00225050360
 protein coding gene Chr10:82851259-82865420 (-)
PWK/PhJ ENSLUMG00010042795
 protein coding gene Chr10:76385012-76399132 (-)
SPRET/EiJ ENSMSPG00010037016
 protein coding gene Chr10:78005019-78019864 (-)
WSB/EiJ ENSIUOG00005050477
 protein coding gene Chr10:76412986-76427173 (-)



Homology
more
  • Human Ortholog
    PLPPR3, phospholipid phosphatase related 3
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PLPPR3, phospholipid phosphatase related 3
  • Synonyms
    LPPR3, LPR3, PRG-2, PRG2
  • Links
    NCBI Gene ID: 79948
    UniProt: Q6T4P5

  • Chr Location
    19p13.3; chr19:812487-823797 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    696
  • Tissues
    18
  • cDNA Data
    67
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000035835 Ensembl Gene Model | MGI Sequence Detail 14160 C57BL/6J ±  kb
transcript ENSMUST00000092325 Ensembl | MGI Sequence Detail 2766 Not Applicable  
polypeptide ENSMUSP00000089979 Ensembl | MGI Sequence Detail 716 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    8 Sequences
  • Protein Ontology
    PR:000009905 phospholipid phosphatase-related protein type 3
    (term hierarchy)
  • InterPro Domains
    IPR043216 Phosphatidic acid phosphatases-like
    IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase
    IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily
  • GlyGen
    Q7TPB0 5 sites, 1 O-linked glycan (2 sites)
Molecular
Reagents
less
  • All nucleic 67
    cDNA 67

    Microarray probesets 2
References
more
  • Summaries
    All 40
    Developmental Gene Expression 5
    Gene Ontology 4
    Phenotypes 10
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:323226 Gross I, et al., Systematic expression analysis of plasticity-related genes in mouse brain development brings PRG4 into play. Dev Dyn. 2022 Apr;251(4):714-728
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory