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Slc26a1 Gene Detail
Summary
  • Symbol
    Slc26a1
  • Name
    solute carrier family 26 (sulfate transporter), member 1
  • Synonyms
    Sat1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385894
    NCBI Gene: 231583
  • Alliance
    genome feature page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:108817744-108823435 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 53.24 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    153 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2385894
 protein coding gene Chr5:108817744-108826246 (-)
129S1/SvImJ ENSMUSG00200021903
 protein coding gene Chr5:102567054-102572748 (-)
A/J ENSMUSG00195030959
 protein coding gene Chr5:102023929-102029623 (-)
AKR/J ENSMUSG00220050605
 protein coding gene Chr5:101574659-101580357 (-)
BALB/cJ ENSMUSG00180041009
 protein coding gene Chr5:102176755-102182449 (-)
C3H/HeJ ENSMUSG00175035147
 protein coding gene Chr5:104225023-104230710 (-)
C57BL/6NJ ENSMUSG00215024301
 protein coding gene Chr5:102220729-102226420 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027527
 protein coding gene Chr5:101552015-101557748 (-)
CAST/EiJ ENSTCUG00005021340
 protein coding gene Chr5:101459013-101464699 (-)
CBA/J ENSMUSG00210039653
 protein coding gene Chr5:102982608-102988295 (-)
DBA/2J ENSMUSG00185045770
 protein coding gene Chr5:105881527-105887220 (-)
FVB/NJ ENSMUSG00205035883
 protein coding gene Chr5:101909245-101914932 (-)
JF1/MsJ ENSUMUG00000013527
 protein coding gene Chr5:108938708-108944398 (-)
LP/J ENSMUSG00230029483
 protein coding gene Chr5:110108085-110113778 (-)
NOD/ShiLtJ ENSMUSG00190028072
 protein coding gene Chr5:101876304-101881997 (-)
NZO/HlLtJ ENSMUSG00225025320
 protein coding gene Chr5:117729954-117735647 (-)
PWK/PhJ ENSLUMG00010037211
 protein coding gene Chr5:100925281-100930964 (-)
SPRET/EiJ ENSMSPG00010045155
 protein coding gene Chr5:104038665-104044312 (-)
WSB/EiJ ENSIUOG00005039574
 protein coding gene Chr5:104604372-104610058 (-)



Homology
more
  • Human Ortholog
    SLC26A1, solute carrier family 26 member 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC26A1, solute carrier family 26 member 1
  • Synonyms
    CAON, CAON1, EDM4, HYSULF, SAT-1, SAT1
  • Links
    NCBI Gene ID: 10861
    UniProt: Q9H2B4

  • Chr Location
    4p16.3; chr4:978991-997659 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human SLC26A1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotypes from 1 allele in 1 genetic background
    3 images
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for disruptions in this gene develop kidney stones and have an increased susceptibility to acetaminophen-induced liver damage.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    32
  • GO References
    12
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    722
  • Tissues
    101
  • cDNA Data
    27
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000046959 Ensembl Gene Model | MGI Sequence Detail 5692 C57BL/6J ±  kb
    transcript ENSMUST00000119270 Ensembl | MGI Sequence Detail 3031 Not Applicable  
    polypeptide ENSMUSP00000113185 Ensembl | MGI Sequence Detail 720 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 29
      cDNA 27
      Primer pair 2

      Microarray probesets 4
    References
    more
    • Summaries
      All 46
      Developmental Gene Expression 4
      Gene Ontology 12
      Phenotypes 13
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:359858 Yoshida Y, et al., Slc26a2-mediated sulfate metabolism is important in tooth development. Dis Model Mech. 2024 Dec 1;17(12)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory