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Rab29 Gene Detail
Summary
  • Symbol
    Rab29
  • Name
    RAB29, member RAS oncogene family
  • Synonyms
    MGC:28972, MGC:36539, Rab7l1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385107
    NCBI Gene: 226422
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:131794962-131800625 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 57.21 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    268 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2385107
 protein coding gene Chr1:131794962-131801003 (+)
129S1/SvImJ ENSMUSG00200006810
 protein coding gene Chr1:129356869-129362533 (+)
A/J ENSMUSG00195040039
 protein coding gene Chr1:128457473-128463145 (+)
AKR/J ENSMUSG00220044439
 protein coding gene Chr1:128288007-128293670 (+)
BALB/cJ ENSMUSG00180036711
 protein coding gene Chr1:129003847-129009514 (+)
C3H/HeJ ENSMUSG00175040244
 protein coding gene Chr1:128702147-128707816 (+)
C57BL/6NJ ENSMUSG00215042056
 protein coding gene Chr1:128717814-128723479 (+)
CAROLI/EiJ no annotation
CAST/EiJ ENSTCUG00005032861
 protein coding gene Chr1:127623090-127628524 (+)
CBA/J ENSMUSG00210027529
 protein coding gene Chr1:128598653-128604318 (+)
DBA/2J ENSMUSG00185029620
 protein coding gene Chr1:132955712-132961374 (+)
FVB/NJ ENSMUSG00205035190
 protein coding gene Chr1:127935024-127940668 (+)
JF1/MsJ ENSUMUG00000041679
 protein coding gene Chr1:132117707-132123121 (+)
LP/J ENSMUSG00230035733
 protein coding gene Chr1:132542917-132548580 (+)
NOD/ShiLtJ ENSMUSG00190028238
 protein coding gene Chr1:128612022-128617691 (+)
NZO/HlLtJ ENSMUSG00225017785
 protein coding gene Chr1:136264122-136269781 (+)
PWK/PhJ ENSLUMG00010026737
 protein coding gene Chr1:127723138-127728550 (+)
SPRET/EiJ ENSMSPG00010042928
 protein coding gene Chr1:130537891-130543293 (+)
WSB/EiJ ENSIUOG00005043546
 protein coding gene Chr1:128345156-128350588 (+)



Homology
more
  • Human Ortholog
    RAB29, RAB29, member RAS oncogene family
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RAB29, RAB29, member RAS oncogene family
  • Synonyms
    RAB7L, RAB7L1
  • Links
    NCBI Gene ID: 8934
    UniProt: O14966

  • Chr Location
    1q32.1; chr1:205767986-205775482 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    13
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    1
  • Gene trapped
    6
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    3 involving Rab29
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    21 strains or lines available
Homozygous null mice show enlarged lysosomes in the kidneys and less efficient cycling of the cargo protein CI-M6PR at the trans-Golgi network resulting in trafficking defects and mis-sorting of lysosomal enzymes.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    73
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    38
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000026433 Ensembl Gene Model | MGI Sequence Detail 5664 C57BL/6J ±  kb
transcript ENSMUST00000027693 Ensembl | MGI Sequence Detail 1226 Not Applicable  
polypeptide ENSMUSP00000027693 Ensembl | MGI Sequence Detail 204 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 38
    cDNA 38

    Microarray probesets 3
References
more
  • Summaries
    All 51
    Gene Ontology 11
    Phenotypes 15
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory