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Gjd3 Gene Detail
Summary
  • Symbol
    Gjd3
  • Name
    gap junction protein, delta 3
  • Synonyms
    connexin 30.2, connexin-30.2, cx30.2, Gja11, Gjc1
Location &
Maps
more
  • Sequence Map
    Chr11:98873006-98873842 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 62.89 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    134 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2384150
 protein coding gene Chr11:98870773-98873846 (-)
129S1/SvImJ ENSMUSG00200051927
 protein coding gene Chr11:96134533-96135369 (-)
A/J ENSMUSG00195049508
 protein coding gene Chr11:95843290-95844126 (-)
AKR/J ENSMUSG00220049807
 protein coding gene Chr11:96101728-96102564 (-)
BALB/cJ ENSMUSG00180043017
 protein coding gene Chr11:96115011-96115847 (-)
C3H/HeJ ENSMUSG00175048265
 protein coding gene Chr11:96108095-96108931 (-)
C57BL/6NJ ENSMUSG00215052298
 protein coding gene Chr11:95691334-95692170 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017104
 protein coding gene Chr11:94899926-94900762 (-)
CAST/EiJ ENSTCUG00005047819
 protein coding gene Chr11:95621418-95622254 (-)
CBA/J ENSMUSG00210052039
 protein coding gene Chr11:95805230-95806066 (-)
DBA/2J ENSMUSG00185049895
 protein coding gene Chr11:96158001-96158837 (-)
FVB/NJ ENSMUSG00205044454
 protein coding gene Chr11:96024948-96025784 (-)
JF1/MsJ ENSUMUG00000037985
 protein coding gene Chr11:96453171-96454007 (-)
LP/J ENSMUSG00230044408
 protein coding gene Chr11:97210877-97211713 (-)
NOD/ShiLtJ ENSMUSG00190041787
 protein coding gene Chr11:96192963-96193799 (-)
NZO/HlLtJ ENSMUSG00225049152
 protein coding gene Chr11:99259308-99260144 (-)
PWK/PhJ ENSLUMG00010047034
 protein coding gene Chr11:96003836-96004672 (-)
SPRET/EiJ ENSMSPG00010048892
 protein coding gene Chr11:96531716-96532552 (-)
WSB/EiJ ENSIUOG00005050194
 protein coding gene Chr11:95961932-95962768 (-)



Homology
more
  • Human Ortholog
    GJD3, gap junction protein delta 3
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GJD3, gap junction protein delta 3
  • Synonyms
    Cx30.2, CX31.9, GJA11, GJC1
  • Links
    NCBI Gene ID: 125111
    UniProt: Q8N144

  • Chr Location
    17q21.2; chr17:40360652-40364737 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 2 alleles in 3 genetic backgrounds
    5 phenotypes from multigenic genotypes
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit accelerated atrioventricular nodal conduction velocity in the heart but no significant alterations in excitability or fast network oscillations in the hippocampus.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    33
  • GO References
    13
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    651
  • Tissues
    8
  • cDNA Data
    3
  • Literature Summary
    10
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000047197 Ensembl Gene Model | MGI Sequence Detail 837 C57BL/6J ±  kb
    transcript ENSMUST00000062931 Ensembl | MGI Sequence Detail 837 Not Applicable  
    polypeptide ENSMUSP00000055246 Ensembl | MGI Sequence Detail 278 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 5
      cDNA 3
      Primer pair 2
      Antibodies 1

      Microarray probesets 1
    References
    more
    • Summaries
      All 51
      Developmental Gene Expression 10
      Gene Ontology 13
      Phenotypes 15
    • Earliest
      J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
    • Latest
      J:350375 Bhattacharyya S, et al., Global chromatin landscapes identify candidate noncoding modifiers of cardiac rhythm. J Clin Invest. 2023 Feb 1;133(3)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory